Anti-NLN Antibody (CAB13112)
- SKU:
- CAB13112
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-NLN Antibody |
| 抗体コード: | CAB13112 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-260 of human NLN (NP_065777.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | HeLa, A-549, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-260 of human NLN (NP_065777.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SSYT VAGR NVLR WDLS PEQI KTRT EELI VQTK QVYD AVGM LGIE EVTY ENCL QALA DVEV KYIV ERTM LDFP QHVS SDKE VRAA STEA DKRL SRFD IEMS MRGD IFER IVHL QETC DLGK IKPE ARRY LEKS IKMG KRNG LHLP EQVQ NEIK SMKK RMSE LCID FNKN LNED DTFL VFSK AELG ALPD DFID SLEK TDDD KYKI TLKY PHYF PVMK KCCI PET |
| 遺伝子ID: | 57486 |
| Uniprot: | Q9BYT8 |
| セルラーロケーション: | Cytoplasm, Mitochondrion intermembrane space |
| 計算された分子量: | 80kDa |
| 観察された分子量: | 80kDa |
| 同義語: | NLN, AGTBP, EP24.16, MEP, MOP |
| バックグラウンド: | This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract. |
| UniProt Protein Function: | NLN: Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. Belongs to the peptidase M3 family. |
| UniProt Protein Details: | Protein type:EC 3.4.24.16; Mitochondrial; Protease Chromosomal Location of Human Ortholog: 5q12.3 Cellular Component: plasma membrane; mitochondrial intermembrane space Molecular Function:metalloendopeptidase activity; metal ion binding; peptide binding Biological Process: proteolysis |
| NCBI Summary: | This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010] |
| UniProt Code: | Q9BYT8 |
| NCBI GenInfo Identifier: | 14149738 |
| NCBI Gene ID: | 57486 |
| NCBI Accession: | NP_065777.1 |
| UniProt Secondary Accession: | Q9BYT8,Q9ULJ4, |
| UniProt Related Accession: | Q9BYT8 |
| Molecular Weight: | 80,652 Da |
| NCBI Full Name: | neurolysin, mitochondrial |
| NCBI Synonym Full Names: | neurolysin (metallopeptidase M3 family) |
| NCBI Official Symbol: | NLN |
| NCBI Official Synonym Symbols: | MEP; MOP; AGTBP; EP24.16 |
| NCBI Protein Information: | neurolysin, mitochondrial; endopeptidase 24.16; microsomal endopeptidase; neurotensin endopeptidase; angiotensin binding protein; angiotensin-binding protein; mitochondrial oligopeptidase M |
| UniProt Protein Name: | Neurolysin, mitochondrial |
| UniProt Synonym Protein Names: | Angiotensin-binding protein; Microsomal endopeptidase; MEP; Mitochondrial oligopeptidase M; Neurotensin endopeptidase |
| Protein Family: | Neurolysin |
| UniProt Gene Name: | NLN |
| UniProt Entry Name: | NEUL_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NLN antibody (CAB13112) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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