Anti-NFIC Antibody (CAB15074)
- SKU:
- CAB15074
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-NFIC Antibody |
抗体コード: | CAB15074 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFIC (NP_005588.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, LO2, MCF-7, DU145, NIH/3T3, mouse liver, mouse skeletal muscle, rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFIC (NP_005588.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MYSS PLCL TQDE FHPF IEAL LPHV RAFA YTWF NLQA RKRK YFKK HEKR MSKD EERA VKDE LLGE KPEV KQKW ASRL LAKL RKDI RPEC REDF VLSI TGKK APGC VLSN PDQK GKMR RIDC LRQA DKVW RLDL VMVI LFKG IPLE STDG ERLV KAAQ CGHP VLCV QPHH IGVA VKEL DLYL AYFV RERD AEQS GSPR TGMG SDQE DSKP ITLD TTDF QESF |
遺伝子ID: | 4782 |
Uniprot: | P08651 |
セルラーロケーション: | Nucleus |
計算された分子量: | 45kDa/47kDa/48kDa/54kDa/55kDa |
観察された分子量: | 60kDa |
同義語: | NFIC, CTF, CTF5, NF-I, NFI |
バックグラウンド: | The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
UniProt Protein Function: | NFI-C: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleolus; nucleus Molecular Function:transcription factor activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | P08651 |
NCBI GenInfo Identifier: | 14195672 |
NCBI Gene ID: | 4782 |
NCBI Accession: | P08651.2 |
UniProt Secondary Accession: | P08651,P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1 A8K1H0, B7Z4U5, B7Z9C3, K7EMU1, |
UniProt Related Accession: | P08651 |
Molecular Weight: | 48,894 Da |
NCBI Full Name: | Nuclear factor 1 C-type |
NCBI Synonym Full Names: | nuclear factor I C |
NCBI Official Symbol: | NFIC |
NCBI Official Synonym Symbols: | CTF; NFI; CTF5; NF-I |
NCBI Protein Information: | nuclear factor 1 C-type |
UniProt Protein Name: | Nuclear factor 1 C-type |
UniProt Synonym Protein Names: | CCAAT-box-binding transcription factor; CTF; Nuclear factor I/C; NF-I/C; NFI-C; TGGCA-binding protein |
Protein Family: | Nuclear factor |
UniProt Gene Name: | NFIC |
UniProt Entry Name: | NFIC_HUMAN |
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