Anti-NFIA Antibody (CAB3258)
- SKU:
- CAB3258
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-NFIA Antibody |
抗体コード: | CAB3258 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-330 of human NFIA (NP_005586.1). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-330 of human NFIA (NP_005586.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AYFV HAAD SSQS ESPS QPSD ADIK DQPE NGHL GFQD SFVT SGVF SVTE LVRV SQTP IAAG TGPN FSLS DLES SSYY SMSP GAMR RSLP STSS TSST KRLK SVED EMDS PGEE PFYT GQGR SPGS GSQS SGWH EVEP GMPS PTTL KKSE KSG |
遺伝子ID: | 4774 |
Uniprot: | Q12857 |
セルラーロケーション: | Nucleus |
計算された分子量: | 54kDa/55kDa/60kDa |
観察された分子量: | 60kDa |
同義語: | NFIA, CTF, NF-I/A, NF1-A, NFI-A, NFI-L, BRMUTD |
バックグラウンド: | This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | NFI-A: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 1p31.3-p31.2 Cellular Component: nucleoplasm; nucleus; cell junction Molecular Function:transcription factor binding; transcription factor activity Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; viral genome replication; DNA replication; response to organic cyclic substance |
NCBI Summary: | This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q12857 |
NCBI GenInfo Identifier: | 14194959 |
NCBI Gene ID: | 4774 |
NCBI Accession: | Q12857.2 |
UniProt Secondary Accession: | Q12857,O00712, P08651, Q14938, |
UniProt Related Accession: | Q12857 |
Molecular Weight: | |
NCBI Full Name: | Nuclear factor 1 A-type |
NCBI Synonym Full Names: | nuclear factor I A |
NCBI Official Symbol: | NFIA |
NCBI Official Synonym Symbols: | CTF; NF1-A; NFI-A; NFI-L; BRMUTD; NF-I/A |
NCBI Protein Information: | nuclear factor 1 A-type |
UniProt Protein Name: | Nuclear factor 1 A-type |
UniProt Synonym Protein Names: | CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein |
UniProt Gene Name: | NFIA |
UniProt Entry Name: | NFIA_HUMAN |
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