Anti-NDUFA2 Antibody (CAB8136)
- SKU:
- CAB8136
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | NDUFA2 Rabbit Polyclonal Antibody |
抗体コード: | CAB8136 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human NDUFA2 (NP_002479.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Mouse heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human NDUFA2 (NP_002479.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAA AASR GVGA KLGL REIR IHLC QRSP GSQG VRDF IEKR YVEL KKAN PDLP ILIR ECSD VQPK LWAR YAFG QETN VPLN NFSA DQVT RALE NVL |
遺伝子ID: | 4695 |
Uniprot: | O43678 |
セルラーロケーション: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein |
計算された分子量: | 8kDa/10kDa |
観察された分子量: | 11kDa |
同義語: | NDUFA2, B8, CD14, CIB8 |
バックグラウンド: | The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | NDUFA2: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
UniProt Protein Details: | Protein type:Mitochondrial; EC 1.6.99.3; Oxidoreductase; EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 5q31.2 Cellular Component: mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex I Molecular Function:NADH dehydrogenase (ubiquinone) activity Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly Disease: Leigh Syndrome |
NCBI Summary: | The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
UniProt Code: | O43678 |
NCBI GenInfo Identifier: | 297206774 |
NCBI Gene ID: | 4695 |
NCBI Accession: | NP_001171941.1 |
UniProt Secondary Accession: | O43678,Q6IAY8, D6RJD6, |
UniProt Related Accession: | O43678 |
Molecular Weight: | 8,491 Da |
NCBI Full Name: | NADH dehydrogenase |
NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase subunit A2 |
NCBI Official Symbol: | NDUFA2 |
NCBI Official Synonym Symbols: | B8; CD14; CIB8 |
NCBI Protein Information: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
UniProt Protein Name: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
UniProt Synonym Protein Names: | Complex I-B8; CI-B8; NADH-ubiquinone oxidoreductase B8 subunit |
Protein Family: | NADH dehydrogenase |
UniProt Gene Name: | NDUFA2 |
UniProt Entry Name: | NDUA2_HUMAN |
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