UniProt Protein Function: | NAT6: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. Belongs to the acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - phenylalanine; Tumor suppressor; Amino Acid Metabolism - tyrosine; Acetyltransferase; EC 2.3.1.-; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - glycerophospholipid Chromosomal Location of Human Ortholog: 3p21.3 |
NCBI Summary: | This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011] |
UniProt Code: | Q93015 |
NCBI GenInfo Identifier: | 25008833 |
NCBI Gene ID: | 24142 |
NCBI Accession: | Q93015.2 |
UniProt Secondary Accession: | Q93015,Q93014, |
UniProt Related Accession: | Q93015 |
Molecular Weight: | 33,831 Da |
NCBI Full Name: | N-acetyltransferase 6 |
NCBI Synonym Full Names: | N-acetyltransferase 6 |
NCBI Official Symbol: | NAT6 |
NCBI Official Synonym Symbols: | FUS2; FUS-2 |
NCBI Protein Information: | N-acetyltransferase 6 |
UniProt Protein Name: | N-acetyltransferase 6 |
UniProt Synonym Protein Names: | Protein fusion-2; Protein fus-2 |
Protein Family: | N-acetyltransferase |
UniProt Gene Name: | NAT6 |
UniProt Entry Name: | NAT6_HUMAN |