Anti-NAPSA Antibody (CAB5594)
- SKU:
- CAB5594
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-NAPSA Antibody |
抗体コード: | CAB5594 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-250 of human NAPSA (NP_004842.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-250 of human NAPSA (NP_004842.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TLIR IPLH RVQP GRRI LNLL RGWR EPAE LPKL GAPS PGDK PIFV PLSN YRDV QYFG EIGL GTPP QNFT VAFD TGSS NLWV PSRR CHFF SVPC WLHH RFDP KASS SFQA NGTK FAIQ YGTG RVDG ILSE DKLT IGGI KGAS VIFG EALW EPSL VFAF AHFD GILG LGFP ILSV EGVR PPMD VLVE QGLL DKPV FSFY LNRD PEEP DGGE LVLG GSDP AHYI PPLT FV |
遺伝子ID: | 9476 |
Uniprot: | O96009 |
セルラーロケーション: | Secreted |
計算された分子量: | 45kDa |
観察された分子量: | 45kDa |
同義語: | NAPSA, KAP, Kdap, NAP1, NAPA, SNAPA, napsin-A, Napsin A |
バックグラウンド: | This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. |
UniProt Protein Function: | NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family. |
UniProt Protein Details: | Protein type:EC 3.4.23.-; Protease; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: extracellular space; lysosome Molecular Function:aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity Biological Process: cellular protein metabolic process; membrane protein proteolysis; protein catabolic process; surfactant homeostasis |
NCBI Summary: | This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016] |
UniProt Code: | O96009 |
NCBI GenInfo Identifier: | 6225749 |
NCBI Gene ID: | 9476 |
NCBI Accession: | O96009.1 |
UniProt Secondary Accession: | O96009,Q8WWD9, |
UniProt Related Accession: | O96009 |
Molecular Weight: | 45,387 Da |
NCBI Full Name: | Napsin-A |
NCBI Synonym Full Names: | napsin A aspartic peptidase |
NCBI Official Symbol: | NAPSA |
NCBI Official Synonym Symbols: | KAP; Kdap; NAP1; NAPA; SNAPA |
NCBI Protein Information: | napsin-A |
UniProt Protein Name: | Napsin-A |
UniProt Synonym Protein Names: | Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02 |
Protein Family: | Napsin |
UniProt Gene Name: | NAPSA |
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