Anti-NANS Antibody (CAB4778)
- SKU:
- CAB4778
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NANS
- Synonyms:
- HEL-S-100
- Synonyms:
- SAS
- Synonyms:
- SEMDCG
- Synonyms:
- SEMDG
Frequently bought together:
Description
| 抗体名: | NANS Rabbit pAb |
| 抗体コード: | CAB4778 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | NANS, HEL-S-100, SAS, SEMDCG, SEMDG |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-359 of human NANS (NP_061819.2). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-549, OVCAR3, A-431 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-359 of human NANS (NP_061819.2). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AELV RSVR LVER ALGS PTKQ LLPC EMAC NEKL GKSV VAKV KIPE GTIL TMDM LTVK VGEP KGYP PEDI FNLV GKKV LVTV EEDD TIME ELVD NHGK KIKS |
| 遺伝子ID: | 54187 |
| Uniprot: | Q9NR45 |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 40kDa |
| UniProt Protein Function: | NANS: Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 2.5.1.57; Transferase; EC 2.5.1.56 Chromosomal Location of Human Ortholog: 9p24.1-p23 Cellular Component: cytoplasm; cytosol Molecular Function:N-acylneuraminate-9-phosphate synthase activity; N-acetylneuraminate synthase activity; N-acylneuraminate cytidylyltransferase activity Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; lipopolysaccharide biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
| NCBI Summary: | This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NR45 |
| NCBI GenInfo Identifier: | 20978759 |
| NCBI Gene ID: | 54187 |
| NCBI Accession: | Q9NR45.2 |
| UniProt Secondary Accession: | Q9NR45,Q8WUV9, Q9BWS6, Q9NVD4, B2RE98, |
| UniProt Related Accession: | Q9NR45 |
| Molecular Weight: | 359 |
| NCBI Full Name: | Sialic acid synthase |
| NCBI Synonym Full Names: | N-acetylneuraminic acid synthase |
| NCBI Official Symbol: | NANS |
| NCBI Official Synonym Symbols: | SAS; HEL-S-100 |
| NCBI Protein Information: | sialic acid synthase; N-acetylneuraminate synthase; sialic acid phosphate synthase; epididymis secretory protein Li 100; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid phosphate synthase |
| UniProt Protein Name: | Sialic acid synthase |
| UniProt Synonym Protein Names: | N-acetylneuraminate synthase (EC:2.5.1.56); N-acetylneuraminate-9-phosphate synthase (EC:2.5.1.57); N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase |
| Protein Family: | Sialic acid synthase |
| UniProt Gene Name: | NANS |
| UniProt Entry Name: | SIAS_HUMAN |