Anti-NANOS3 Antibody (CAB17925)
- SKU:
- CAB17925
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-NANOS3 Antibody |
| 抗体コード: | CAB17925 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human NANOS3 (NP_001092092.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human NANOS3 (NP_001092092.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MGTF DLWT DYLG LAHL VRAL SGKE GPET RLSP QPEP EPML EPVS ALEP MPAP ESVP VPGP KDQK RSLE SSPA PERL CSFC KHNG ESRA IYQS HVLK DEAG RVLC PILR DYVC PQCG ATRE RAHT RRFC PLTG QGYT SVYS HTTR NSAG KKLV RPDK AKTQ DTGH RRGG GGGA GFRG AGKS EPSP SCSP SMST |
| 遺伝子ID: | 342977 |
| Uniprot: | P60323 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | NANOS3, NANOS1L, NOS3, ZC2HC12C |
| バックグラウンド: |
| UniProt Protein Function: | NANOS3: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. Belongs to the nanos family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; Cell development/differentiation Chromosomal Location of Human Ortholog: 19p13.13 Cellular Component: perinuclear region of cytoplasm; stress granule; cytoplasm; nucleus Molecular Function:protein binding; zinc ion binding; RNA binding Biological Process: oogenesis; regulation of translation; regulation of cell cycle; multicellular organismal development; negative regulation of translation; spermatogenesis; germ cell development |
| UniProt Code: | P60323 |
| NCBI GenInfo Identifier: | 41688563 |
| NCBI Gene ID: | 342977 |
| NCBI Accession: | P60323.1 |
| UniProt Related Accession: | P60323 |
| Molecular Weight: | Observed Molecular Weight: (Observed)18kD.Predicted Molecular Weight: (Calculated)19kDa. |
| NCBI Full Name: | Nanos homolog 3 |
| NCBI Synonym Full Names: | nanos C2HC-type zinc finger 3 |
| NCBI Official Symbol: | NANOS3 |
| NCBI Official Synonym Symbols: | NOS3; NANOS1L; ZC2HC12C |
| NCBI Protein Information: | nanos homolog 3 |
| UniProt Protein Name: | Nanos homolog 3 |
| Protein Family: | Nanos |
| UniProt Gene Name: | NANOS3 |
| UniProt Entry Name: | NANO3_HUMAN |