Anti-N6-methyladenosine / m6A Antibody (CAB19136)

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SKU:
CAB19136
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Reactivity:
Other (Wide Range)
Host Species:
Mouse
Isotype:
IgG
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-N6-methyladenosine / m6A Antibody
抗体コード:CAB19136
抗体サイズ:20uL, 50uL, 100uL
申し込み:DB
反応性:Human, Mouse, Rat, Other (Wide Range)
宿主種:Mouse
免疫原:Chemical compounds corresponding to N6-methyladenosine / m6A.
申し込み:DB
推奨希釈:DB 1:500 - 1:2000
反応性:Human, Mouse, Rat, Other (Wide Range)
ポジティブサンプル:
免疫原:Chemical compounds corresponding to N6-methyladenosine / m6A.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:
Uniprot:
セルラーロケーション:
計算された分子量:
観察された分子量:
Anti-N6-methyladenosine / m6A Antibody (CAB19136)`- N6-methyladenosine / m6A Mouse mAb (CAB19136)
同義語:N6-methyladenosine, m6A
バックグラウンド:Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)
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