Anti-N6-methyladenosine / m6A Antibody (CAB17924)
- SKU:
- CAB17924
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Reactivity:
- Other (Wide Range)
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-N6-methyladenosine / m6A Antibody |
| 抗体コード: | CAB17924 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF IP Nucleotide Array DB |
| 反応性: | Human, Mouse, Rat, Other (Wide Range) |
| 宿主種: | Rabbit |
| 免疫原: | Chemical compounds corresponding to N6-methyladenosine / m6A. |
| 申し込み: | IF IP Nucleotide Array DB |
| 推奨希釈: | DB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat, Other (Wide Range) |
| ポジティブサンプル: | Arabidopsis |
| 免疫原: | Chemical compounds corresponding to N6-methyladenosine / m6A. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | |
| Uniprot: | |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: |
 | `- N6-methyladenosine / m6A Rabbit pAb (CAB17924) |
| 同義語: | N6-methyladenosine, m6A |
| バックグラウンド: | Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466) |