Anti-MYOCD Antibody (CAB16159)
- SKU:
- CAB16159
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-MYOCD Antibody |
抗体コード: | CAB16159 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 650-750 of human MYOCD (NP_705832.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | Rat heart |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 650-750 of human MYOCD (NP_705832.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SLPP SPNN PHFL PSSS GAQG EGHR VSSP ISSQ VCTA QMAG LHSS DKVG PKFS IPSP TFSK SSSA ISEV TQPP SYED AVKQ QMTR SQQM DELL DVLI ESGE M |
遺伝子ID: | 93649 |
Uniprot: | Q8IZQ8 |
セルラーロケーション: | Nucleus |
計算された分子量: | 73kDa/101kDa/106kDa |
観察された分子量: | 102kDa |
同義語: | MYOCD, MYCD, myocardin |
バックグラウンド: | This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). |
NCBI Summary: | This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | Q8IZQ8 |
NCBI GenInfo Identifier: | 54306542 |
NCBI Gene ID: | 93649 |
NCBI Accession: | AAV33439.1 |
UniProt Secondary Accession: | Q8IZQ8,Q5UBU5, Q8N7Q1, |
UniProt Related Accession: | Q8IZQ8 |
Molecular Weight: | 73,183 Da |
NCBI Full Name: | myocardin |
NCBI Synonym Full Names: | myocardin |
NCBI Official Symbol: | MYOCD |
NCBI Official Synonym Symbols: | MYCD |
NCBI Protein Information: | myocardin |
UniProt Protein Name: | Myocardin |
Protein Family: | Myocilin |
UniProt Gene Name: | MYOCD |
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