Anti-MYL6B Antibody (CAB18102)[KO Validated]

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SKU:
CAB18102
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-MYL6B Antibody [KO Validated]
抗体コード:CAB18102
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human MYL6B (NP_002466.1).
申し込み:WB
推奨希釈:WB 1:200 - 1:500
反応性:Human, Mouse, Rat
ポジティブサンプル:293T
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human MYL6B (NP_002466.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MPPK KDVP VKKP AGPS ISKP AAKP AAAG APPA KTKA EPAV PQAP QKTQ EPPV DLSK VVIE FNKD QLEE FKEA FELF DRVG DGKI LYSQ CGDV MRAL GQNP TNAE VLKV LGNP KSDE LKSR RVDF ETFL PMLQ AVAK NRGQ GTYE DYLE GFRV FDKE GNGK VMGA ELRH VLTT LGEK MTEE EVET VLAG HEDS NGCI NYEA FLKH ILSV
遺伝子ID:140465
Uniprot:P14649
セルラーロケーション:
計算された分子量:22kDa
観察された分子量:25kDa
Anti-MYL6B Antibody [KO Validated] (CAB18102)Western blot analysis of extracts from normal (control) and MYL6B knockout (KO) 293T cells, using MYL6B antibody (CAB18102) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
同義語:MYL6B, MLC1SA
バックグラウンド:Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:MYL6B: Regulatory light chain of myosin. Does not bind calcium.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Contractile

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytosol; muscle myosin complex; myosin complex; unconventional myosin complex

Molecular Function:motor activity; protein binding; structural constituent of muscle

Biological Process: muscle contraction; muscle filament sliding; skeletal muscle development

NCBI Summary:Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
UniProt Code:P14649
NCBI GenInfo Identifier:127153
NCBI Gene ID:140465
NCBI Accession:P14649.1
UniProt Related Accession:P14649
Molecular Weight:22,764 Da
NCBI Full Name:Myosin light chain 6B
NCBI Synonym Full Names:myosin light chain 6B
NCBI Official Symbol:MYL6B  
NCBI Official Synonym Symbols:MLC1SA  
NCBI Protein Information:myosin light chain 6B
UniProt Protein Name:Myosin light chain 6B
UniProt Synonym Protein Names:Myosin light chain 1 slow-twitch muscle A isoform; MLC1sa; Smooth muscle and nonmuscle myosin light chain alkali 6B
Protein Family:Myosin
UniProt Gene Name:MYL6B  
UniProt Entry Name:MYL6B_HUMAN
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