Anti-MYBPC1 Antibody (CAB8348)
- SKU:
- CAB8348
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MYBPC1 Antibody |
| 抗体コード: | CAB8348 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 942-1171 of human MYBPC1 (NP_002456.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse skeletal muscle, Rat spinal cord |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 942-1171 of human MYBPC1 (NP_002456.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PQIV KIED VWGE NVAL TWTP PKDD GNAA ITGY TIQK ADKK SMEW FTVI EHYH RTSA TITE LVIG NEYY FRVF SENM CGLS EDAT MTKE SAVI ARDG KIYK NPVY EDFD FSEA PMFT QPLV NTYA IAGY NATL NCSV RGNP KPKI TWMK NKVA IVDD PRYR MFSN QGVC TLEI RKPS PYDG GTYC CKAV NDLG TVEI ECKL EVKV IYQG VNTP GQPV FLEG QQQS LHNK DF |
| 遺伝子ID: | 4604 |
| Uniprot: | Q00872 |
| セルラーロケーション: | |
| 計算された分子量: | 126kDa/127kDa/128kDa/129kDa/131kDa |
| 観察された分子量: | 150kDa |
| 同義語: | MYBPC1, LCCS4, MYBPCC, MYBPCS, slow-type |
| バックグラウンド: | This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. |
| NCBI Summary: | This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q00872 |
| NCBI GenInfo Identifier: | 6166597 |
| NCBI Gene ID: | 4604 |
| NCBI Accession: | Q00872.2 |
| UniProt Secondary Accession: | Q00872,Q15497, Q17RR7, Q569K7, B4DKR5, B7Z8G8, B7ZL02 B7ZL09, B7ZL10, E7ESM5, E7EWS6, G3XAE8, |
| UniProt Related Accession: | Q00872 |
| Molecular Weight: | 129,074 Da |
| NCBI Full Name: | Myosin-binding protein C, slow-type |
| NCBI Synonym Full Names: | myosin binding protein C, slow type |
| NCBI Official Symbol: | MYBPC1 |
| NCBI Official Synonym Symbols: | LCCS4; MYBPCC; MYBPCS |
| NCBI Protein Information: | myosin-binding protein C, slow-type |
| UniProt Protein Name: | Myosin-binding protein C, slow-type |
| UniProt Synonym Protein Names: | C-protein, skeletal muscle slow isoform |
| Protein Family: | Myosin-binding protein |
| UniProt Gene Name: | MYBPC1 |
| UniProt Entry Name: | MYPC1_HUMAN |
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