Anti-MTERFD3 Antibody (CAB8518)
- SKU:
- CAB8518
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-MTERFD3 Antibody |
| 抗体コード: | CAB8518 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MTERFD3 (NP_079474.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, U-251MG, NCI-H460, Mouse liver, Mouse kidney, Rat heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MTERFD3 (NP_079474.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MLWK LLLR SQSC RLCS FRKM RSPP KYRP FLAC FTYT TDKQ SSKE NTRT VEKL YKCS VDIR KIRR LKGW VLLE DETY VEEI ANIL QELG ADET AVAS ILER CPEA IVCS PTAV NTQR KLWQ LVCK NEEE LIKL IEQF PESF FTIK DQEN QKLN VQFF QELG LKNV VISR LLTA APNV FHNP VEKN KQMV RILQ ESYL DVGG SEAN MKVW LLKL LSQN PFIL LNSP TAIK ETLE FLQE QGFT SFEI LQLL SK |
| 遺伝子ID: | 80298 |
| Uniprot: | Q49AM1 |
| セルラーロケーション: | Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid |
| 計算された分子量: | 44kDa |
| 観察された分子量: | 38-44kDa |
| 同義語: | MTERF2, MTERFD3, mTERFL |
| バックグラウンド: |
| UniProt Protein Function: | MTERFD3: Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function. Belongs to the mTERF family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12q24.1 Cellular Component: mitochondrial matrix Molecular Function:protein homodimerization activity; double-stranded DNA binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| UniProt Code: | Q49AM1 |
| NCBI GenInfo Identifier: | 21314736 |
| NCBI Gene ID: | 80298 |
| NCBI Accession: | NP_079474 |
| UniProt Related Accession: | Q49AM1 |
| Molecular Weight: | 42kDa |
| NCBI Full Name: | transcription termination factor 2, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial transcription termination factor 2 |
| NCBI Official Symbol: | MTERF2 |
| NCBI Official Synonym Symbols: | mTERFL; MTERFD3 |
| NCBI Protein Information: | transcription termination factor 2, mitochondrial |
| UniProt Protein Name: | Transcription termination factor 2, mitochondrial |
| UniProt Synonym Protein Names: | Mitochondrial transcription termination factor 2; mTERF2; mTERFL; Mitochondrial transcription termination factor-like protein; mTERF domain-containing protein 3, mitochondrial |
| Protein Family: | Transcription termination factor |
| UniProt Gene Name: | MTERF2 |
| UniProt Entry Name: | MTEF2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MTERFD3 antibody (CAB8518) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunohistochemistry of paraffin-embedded mouse kidney using MTERFD3 antibody (CAB8518) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using MTERFD3 antibody (CAB8518) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using MTERFD3 antibody (CAB8518) at dilution of 1:100 (40x lens). |
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