Anti-MTCO2 Antibody (CAB3843)
- SKU:
- CAB3843
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MTCO2 Antibody |
| 抗体コード: | CAB3843 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human MTCO2 |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, HepG2, K-562 |
| 免疫原: | A synthesized peptide derived from human MTCO2 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 4513 |
| Uniprot: | P00403 |
| セルラーロケーション: | |
| 計算された分子量: | 21kDa |
| 観察された分子量: | 20KDa |
| 同義語: | COII, MTCO2 |
| バックグラウンド: |
| UniProt Protein Function: | COX2: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Defects in MT-CO2 are a cause of mitochondrial complex IV deficiency (MT-C4D); also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome. Belongs to the cytochrome c oxidase subunit 2 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Oxidoreductase; Membrane protein, multi-pass; Energy Metabolism - oxidative phosphorylation; Mitochondrial; EC 1.9.3.1 Chromosomal Location of Human Ortholog: - Disease: Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-like Episodes |
| UniProt Code: | P00403 |
| NCBI GenInfo Identifier: | 117020 |
| NCBI Gene ID: | |
| NCBI Accession: | P00403.1 |
| Molecular Weight: | |
| NCBI Full Name: | Cytochrome c oxidase subunit 2 |
| UniProt Protein Name: | Cytochrome c oxidase subunit 2 |
| UniProt Synonym Protein Names: | Cytochrome c oxidase polypeptide II |
| UniProt Gene Name: | MT-CO2 |
| UniProt Entry Name: | COX2_HUMAN |
 | Western blot - MTCO2 Rabbit mAb (CAB3843) |
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