Anti-MSRB2 Antibody (CAB8364)
- SKU:
- CAB8364
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MSRB2 Antibody |
| 抗体コード: | CAB8364 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-182 of human MSRB2 (NP_036360.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse heart, Mouse kidney, Mouse brain, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-182 of human MSRB2 (NP_036360.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GLTL GTAP RRAV RGQA GGGG PGTG PGLG EAGS LATC ELPL AKSE WQKK LTPE QFYV TREK GTEP PFSG IYLN NKEA GMYH CVCC DSPL FSSE KKYC SGTG WPSF SEAH GTSG SDES HTGI LRRL DTSL GSAR TEVV CKQC EAHL GHVF PDGP GPNG QRFC INSV ALKF KPRK H |
| 遺伝子ID: | 22921 |
| Uniprot: | Q9Y3D2 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 19kDa |
| 観察された分子量: | 20kDa |
| 同義語: | MSRB2, CBS-1, CBS1, CGI-131, MSRB, PILB |
| バックグラウンド: |
| UniProt Protein Function: | MSRB2: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. Belongs to the MsrB Met sulfoxide reductase family. |
| UniProt Protein Details: | Protein type:EC 1.8.4.-; Oxidoreductase; Mitochondrial; Transcription factor Chromosomal Location of Human Ortholog: 10p12 Cellular Component: mitochondrion Molecular Function:zinc ion binding; peptide-methionine (R)-S-oxide reductase activity; actin binding; transcription factor activity Biological Process: protein repair; regulation of transcription, DNA-dependent; actin filament polymerization; response to oxidative stress |
| UniProt Code: | Q9Y3D2 |
| NCBI GenInfo Identifier: | 182676405 |
| NCBI Gene ID: | 22921 |
| NCBI Accession: | Q9Y3D2.2 |
| UniProt Secondary Accession: | Q9Y3D2,Q17R44, Q4G1C7, Q9Y5W6, |
| UniProt Related Accession: | Q9Y3D2 |
| Molecular Weight: | 19,536 Da |
| NCBI Full Name: | Methionine-R-sulfoxide reductase B2, mitochondrial |
| NCBI Synonym Full Names: | methionine sulfoxide reductase B2 |
| NCBI Official Symbol: | MSRB2 |
| NCBI Official Synonym Symbols: | CBS1; MSRB; PILB; CBS-1; CGI-131 |
| NCBI Protein Information: | methionine-R-sulfoxide reductase B2, mitochondrial; pilin-like transcription factor |
| UniProt Protein Name: | Methionine-R-sulfoxide reductase B2, mitochondrial |
| Protein Family: | Methionine-R-sulfoxide reductase |
| UniProt Gene Name: | MSRB2 |
| UniProt Entry Name: | MSRB2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MSRB2 antibody (CAB8364) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunohistochemistry of paraffin-embedded human lung cancer using MSRB2 Rabbit pAb (CAB8364) at dilution of 1:200 (40x lens). |
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