Anti-MSI1 Antibody (CAB2609)
- SKU:
- CAB2609
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MSI1 Antibody |
抗体コード: | CAB2609 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSI1 (NP_002433.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SH-SY5Y, 293T, Mouse brain |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSI1 (NP_002433.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | METD APQP GLAS PDSP HDPC KMFI GGLS WQTT QEGL REYF GQFG EVKE CLVM RDPL TKRS RGFG FVTF MDQA GVDK VLAQ SRHE LDSK TIDP KVAF PRRA |
遺伝子ID: | 4440 |
Uniprot: | O43347 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 39kDa |
観察された分子量: | 42KDa |
同義語: | MSI1 |
バックグラウンド: | This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. |
UniProt Protein Function: | Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family. |
UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 12q24 Molecular Function:RNA binding Biological Process: nervous system development |
NCBI Summary: | This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008] |
UniProt Code: | O43347 |
NCBI GenInfo Identifier: | 51316193 |
NCBI Gene ID: | 4440 |
NCBI Accession: | O43347.1 |
UniProt Secondary Accession: | O43347,Q96PU0, Q96PU1, Q96PU2, Q96PU3, |
UniProt Related Accession: | O43347 |
Molecular Weight: | 39,125 Da |
NCBI Full Name: | RNA-binding protein Musashi homolog 1 |
NCBI Synonym Full Names: | musashi RNA binding protein 1 |
NCBI Official Symbol: | MSI1 |
NCBI Protein Information: | RNA-binding protein Musashi homolog 1 |
UniProt Protein Name: | RNA-binding protein Musashi homolog 1 |
Protein Family: | RNA-binding protein |
UniProt Gene Name: | MSI1 |
UniProt Entry Name: | MSI1H_HUMAN |
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