Anti-MRPS18C Antibody (CAB18453)
- SKU:
- CAB18453
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
抗体名: | Anti-MRPS18C Antibody |
抗体コード: | CAB18453 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human MRPS18C. |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, HepG2, 293T |
免疫原: | Recombinant protein of human MRPS18C. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 51023 |
Uniprot: | Q9Y3D5 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 15kDa |
同義語: | CGI-134, MRP-S18-1, MRP-S18-c, MRPS18-1, S18mt-c, mrps18-c, MRPS18C |
バックグラウンド: |
UniProt Protein Function: | MiscellaneousThere are 3 mitochondrial isoforms of bS18 in mammalia, localizing to 3 distinct sites in the mitoribosome. bS18m (bs18c, this protein) binds to the same site as bacterial bS18, mS40 (bS18b) binds to a novel location of the 28S small subunit, and mL66 (bS18a) binds to the 39S large subunit. |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y3D5 |
NCBI GenInfo Identifier: | 663071184 |
NCBI Gene ID: | 51023 |
NCBI Accession: | NP_001284698.1 |
UniProt Related Accession: | Q9Y3D5 |
Molecular Weight: | 16 KD |
NCBI Full Name: | 28S ribosomal protein S18c, mitochondrial isoform 3 |
NCBI Synonym Full Names: | mitochondrial ribosomal protein S18C |
NCBI Official Symbol: | MRPS18C |
NCBI Official Synonym Symbols: | CGI-134; S18mt-c; MRPS18-1; mrps18-c; MRP-S18-1; MRP-S18-c |
NCBI Protein Information: | 28S ribosomal protein S18c, mitochondrial |
UniProt Protein Name: | 28S ribosomal protein S18c, mitochondrial |
UniProt Synonym Protein Names: | 28S ribosomal protein S18-1, mitochondrial; MRP-S18-1; Mitochondrial small ribosomal subunit protein bS18c |
Protein Family: | 28S ribosomal protein |
UniProt Gene Name: | MRPS18C |