Anti-MRPL46 Antibody (CAB15428)
- SKU:
- CAB15428
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-MRPL46 Antibody |
抗体コード: | CAB15428 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human MRPL46 (NP_071446.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human MRPL46 (NP_071446.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAP VRRT LLGV AGGW RRFE RLWA GSLS SRSL ALAA APSS NGSP WRLL GALC LQRP PVVS KPLT PLQE EMAS LLQQ IEIE RSLY SDHE LRAL DENQ RLAK KKAD LHDE EDEQ DILL AQDL EDMW EQKF LQFK LGAR ITEA DEKN DRTS LNRK LDRN LVLL VREK FGDQ DVWI LPQA EWQP GETL RGTA ERTL ATLS ENNM EAKF LGNA PCGH YTFK FPQA MRTE SNLG AKVF FFKA LLLT GDFS QAGN KGHH VWVT KDEL GDYL KPKY LAQV RRFV SDL |
遺伝子ID: | 26589 |
Uniprot: | Q9H2W6 |
セルラーロケーション: | Mitochondrion |
計算された分子量: | 31kDa |
観察された分子量: | 32kDa |
同義語: | MRPL46, C15orf4, LIECG2, P2ECSL |
バックグラウンド: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. |
UniProt Protein Function: | MRPL46: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Ribosomal; Translation; Mitochondrial Chromosomal Location of Human Ortholog: 15q25.3 Cellular Component: cell junction; mitochondrial inner membrane; mitochondrial large ribosomal subunit; mitochondrion; nucleoplasm Molecular Function:structural constituent of ribosome |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H2W6 |
NCBI GenInfo Identifier: | 52783325 |
NCBI Gene ID: | 26589 |
NCBI Accession: | Q9H2W6.1 |
UniProt Secondary Accession: | Q9H2W6,Q9HBU8, B2RD75, |
UniProt Related Accession: | Q9H2W6 |
Molecular Weight: | 31,705 Da |
NCBI Full Name: | 39S ribosomal protein L46, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein L46 |
NCBI Official Symbol: | MRPL46 |
NCBI Official Synonym Symbols: | LIECG2; P2ECSL; C15orf4 |
NCBI Protein Information: | 39S ribosomal protein L46, mitochondrial |
UniProt Protein Name: | 39S ribosomal protein L46, mitochondrial |
UniProt Synonym Protein Names: | P2ECSL |
Protein Family: | 39S ribosomal protein |
UniProt Gene Name: | MRPL46 |
UniProt Entry Name: | RM46_HUMAN |
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