Anti-MRPL39 Antibody (CAB10023)
- SKU:
- CAB10023
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MRPL39 Antibody |
| 抗体コード: | CAB10023 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-338 of human MRPL39 (NP_059142.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:4000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | DU145, K-562, A-431, 293T, Mouse liver, Mouse heart, Mouse kidney, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-338 of human MRPL39 (NP_059142.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ELTE MRND LFNK EKAR QLSL TPRT EKIE VKHV GKTD PGTV FVMN KNIS TPYS CAMH LSEW YCRK SILA LVDG QPWD MYKP LTKS CEIK FLTF KDCD PGEV NKAY WRSC AMMM GCVI ERAF KDEY MVNL VRAP EVPV ISGA FCYD VVLD SKLD EWMP TKEN LRSF TKDA HALI YKDL PFET LEVE AKVA LEIF QHSK YKVD FIEE KASQ NPER IVKL HRIG DFID VSEG PLIP RTSI CFQY EVSA VHNL QPTQ PSLI RRFQ GVSL PVHL RAHF TIWD KLLE RSRK MVTE DQSK ATEE CTST |
| 遺伝子ID: | 54148 |
| Uniprot: | Q9NYK5 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 38kDa/40kDa |
| 観察された分子量: | 38kDa |
| 同義語: | MRPL39, C21orf92, L39mt, MRP-L5, MRPL5, MSTP003, PRED22, PRED66, RPML5 |
| バックグラウンド: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. |
| UniProt Protein Function: | MRPL39: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Translation; Ribosomal Chromosomal Location of Human Ortholog: 21q21.3 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:ligase activity, forming aminoacyl-tRNA and related compounds; proline-tRNA ligase activity; RNA binding Biological Process: mitochondrial genome maintenance; prolyl-tRNA aminoacylation; tRNA aminoacylation for protein translation |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NYK5 |
| NCBI GenInfo Identifier: | 296452977 |
| NCBI Gene ID: | 54148 |
| NCBI Accession: | Q9NYK5.3 |
| UniProt Secondary Accession: | Q9NYK5,Q32Q74, Q5QTR3, Q96Q65, Q9BSQ7, Q9BZV6, Q9NX44 C9JYA5, |
| UniProt Related Accession: | Q9NYK5 |
| Molecular Weight: | 40,458 Da |
| NCBI Full Name: | 39S ribosomal protein L39, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L39 |
| NCBI Official Symbol: | MRPL39 |
| NCBI Official Synonym Symbols: | L39mt; MRPL5; RPML5; MRP-L5; PRED22; PRED66; MSTP003; C21orf92 |
| NCBI Protein Information: | 39S ribosomal protein L39, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L39, mitochondrial |
| UniProt Synonym Protein Names: | 39S ribosomal protein L5, mitochondrial; L5mt; MRP-L5 |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL39 |
| UniProt Entry Name: | RM39_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MRPL39 antibody (CAB10023) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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