Anti-MRPL2 Antibody (CAB14404)
- SKU:
- CAB14404
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MRPL2 Antibody |
| 抗体コード: | CAB14404 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human MRPL2 (NP_057034.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse kidney, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human MRPL2 (NP_057034.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MALC ALTR ALRS LNLA PPTV AAPA PSLF PAAQ MMNN GLLQ QPSA LMLL PCRP VLTS VALN ANFV SWKS RTKY TITP VKMR KSGG RDHT GRIR VHGI GGGH KQRY RMID FLRF RPEE TKSG PFEE KVIQ VRYD PCRS ADIA LVAG GSRK RWII ATEN MQAG DTIL NSNH IGRM AVAA REGD AHPL GALP VGTL INNV ESEP GRGA QYIR AAGT CGVL LRKV NGTA IIQL PSKR QMQV LETC VATV GRVS NVDH NKRV IGKA GRNR WLGK RPNS GRWH RKGG WAGR KIRP LPPM KSYV KLPS ASAQ S |
| 遺伝子ID: | 51069 |
| Uniprot: | Q5T653 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 33kDa |
| 観察された分子量: | 33kDa |
| 同義語: | MRPL2, CGI-22, MRP-L14, RPML14 |
| バックグラウンド: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| UniProt Protein Function: | MRPL2: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; Mitochondrial; RNA-binding; Motility/polarity/chemotaxis; Translation Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit Molecular Function:structural constituent of ribosome Biological Process: mitochondrial translation |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q5T653 |
| NCBI GenInfo Identifier: | 118573672 |
| NCBI Gene ID: | 51069 |
| NCBI Accession: | Q5T653.2 |
| UniProt Secondary Accession: | Q5T653,Q8WUL1, Q96Q56, Q9Y311, B2RC56, |
| UniProt Related Accession: | Q5T653 |
| Molecular Weight: | 33,301 Da |
| NCBI Full Name: | 39S ribosomal protein L2, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L2 |
| NCBI Official Symbol: | MRPL2 |
| NCBI Official Synonym Symbols: | CGI-22; RPML14; MRP-L14 |
| NCBI Protein Information: | 39S ribosomal protein L2, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L2, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL2 |
| UniProt Entry Name: | RM02_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MRPL2 antibody (CAB14404) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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