Anti-MPP7 Antibody (CAB16598)
- SKU:
- CAB16598
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MPP7 Antibody |
抗体コード: | CAB16598 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RLAL RRPE ILVQ PLKV SNRK SSGF RKSF RLSR KDKK TNKS MYEC KKSD QYDT ADVP TYEE VTPY RRQT NEKY RLVV LVGP VGVG LNEL KRKL LISD TQHY GVTV PHTT RARR SQES DGVE YIFI SKHL FETD VQNN KFIE YGEY KNNY YGTS IDSV RSVL AKNK VCLL DVQP HTVK HLRT LEFK PYVI FIKP PSIE RLRE TRKN AKII SSRD DQGA AKPF TEED FQEM IKSA QIME SQYG HLFD KIII NDDL TVAF NELK TTFD KLET ETHW VPVS WLHS |
遺伝子ID: | 143098 |
Uniprot: | Q5T2T1 |
セルラーロケーション: | Cell junction, Membrane, Peripheral membrane protein, adherens junction, tight junction |
計算された分子量: | 42kDa/65kDa |
観察された分子量: | 55kDa |
同義語: | MPP7 |
バックグラウンド: | The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | MPP7: Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. Belongs to the MAGUK family. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 10p12.1 Cellular Component: adherens junction; tight junction; mitochondrion; cell junction Molecular Function:protein domain specific binding; protein binding; protein heterodimerization activity; protein complex scaffold Biological Process: positive regulation of protein complex assembly; positive regulation of signal transduction; establishment of cell polarity |
NCBI Summary: | The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
UniProt Code: | Q5T2T1 |
NCBI GenInfo Identifier: | 74762233 |
NCBI Gene ID: | 143098 |
NCBI Accession: | Q5T2T1.1 |
UniProt Related Accession: | Q5T2T1 |
Molecular Weight: | |
NCBI Full Name: | MAGUK p55 subfamily member 7 |
NCBI Synonym Full Names: | membrane palmitoylated protein 7 |
NCBI Official Symbol: | MPP7 |
NCBI Protein Information: | MAGUK p55 subfamily member 7 |
UniProt Protein Name: | MAGUK p55 subfamily member 7 |
Protein Family: | MAGUK p55 subfamily |
UniProt Gene Name: | MPP7 |
UniProt Entry Name: | MPP7_HUMAN |
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