Anti-MPP2 Antibody (CAB6659)
- SKU:
- CAB6659
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MPP2 Antibody |
抗体コード: | CAB6659 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MPP2 (NP_005365.3). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MPP2 (NP_005365.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MPVA ATNS ETAM QQVL DNLG SLPS ATGA AELD LIFL RGIM ESPI VRSL AKAH ERLE ETKL EAVR DNNL ELVQ EILR DLAH VAEQ SSTA AELA HILQ EPHF QSLL ETHD SVAS KTYE TPPP SPGL DPTF SNQP VPPD AVRM VGIR KTAG EHLG VTFR VEGG ELVI ARIL HGGM VAQQ GLLH VGDI IKEV NGQP VGSD PRAL QELL RNAS GSVI LKIL PSYQ EPHL PRQV FV |
遺伝子ID: | 4355 |
Uniprot: | Q14168 |
セルラーロケーション: | |
計算された分子量: | 46kDa/60kDa/61kDa/63kDa/64kDa/66kDa |
観察された分子量: | 68kDa |
同義語: | MPP2, DLG2 |
バックグラウンド: | Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. |
UniProt Protein Function: | MPP2: a protein of the MAGUK family. Contains one guanylate kinase-like domain, one SH3 domain, one PDZ domain, and two L27 domains. L27 domains are foun CASK in receptor targeting proteins including Lin-2, -4, -5, -6 and -7C, as well as the protein kinases. Three isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 17q12-q21 Cellular Component: membrane; integral to plasma membrane Molecular Function:guanylate kinase activity; PDZ domain binding Biological Process: signal transduction; nucleotide phosphorylation |
NCBI Summary: | Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14168 |
NCBI GenInfo Identifier: | 290457681 |
NCBI Gene ID: | 4355 |
NCBI Accession: | Q14168.3 |
UniProt Secondary Accession: | Q14168,Q53ES9, Q5CZB9, Q9BQJ2, B4DGE9, B4DRJ0, B7Z3G8 E7EV80, E7EV91, E7EX01, |
UniProt Related Accession: | Q14168 |
Molecular Weight: | 576 |
NCBI Full Name: | MAGUK p55 subfamily member 2 |
NCBI Synonym Full Names: | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
NCBI Official Symbol: | MPP2 |
NCBI Official Synonym Symbols: | DLG2 |
NCBI Protein Information: | MAGUK p55 subfamily member 2; discs large, homolog 2 |
UniProt Protein Name: | MAGUK p55 subfamily member 2 |
UniProt Synonym Protein Names: | Discs large homolog 2; Protein MPP2 |
Protein Family: | MAGUK p55 subfamily |
UniProt Gene Name: | MPP2 |
UniProt Entry Name: | MPP2_HUMAN |
View AllClose