Anti-MORC2 Antibody (CAB17641)
- SKU:
- CAB17641
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-MORC2 Antibody |
| 抗体コード: | CAB17641 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-250 of human MORC2 (NP_055756.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, 293T, Mouse thymus, Mouse testis, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-250 of human MORC2 (NP_055756.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EDTM TCLF LSRT FHEE EGID EVIV PLPT WNAR TREP VTDN VEKF AIET ELIY KYSP FRTE EEVM TQFM KIPG DSGT LVII FNLK LMDN GEPE LDII SNPR DIQM AETS PEGT KPER RSFR AYAA VLYI DPRM RIFI HGHK VQTK RLSC CLYK PRMY KYTS SRFK TRAE QEVK KAEH VARI AEEK AREA ESK |
| 遺伝子ID: | 22880 |
| Uniprot: | Q9Y6X9 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 118kDa |
 | Western blot - MORC2 Polyclonal Antibody (CAB17641) |
| 同義語: | CMT2Z, ZCW3, ZCWCC1, MORC2 |
| バックグラウンド: | This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
| UniProt Protein Function: | MORC2: a protein containing a Zinc finger CW-type coiled-coil domain and a HATPase_c domain. HATPase_c domains are found in several ATP-binding proteins including histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, and DNA mismatch repair proteins. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: cytoplasm; nucleus |
| NCBI Summary: | This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
| UniProt Code: | Q9Y6X9 |
| NCBI GenInfo Identifier: | 114152840 |
| NCBI Gene ID: | 22880 |
| NCBI Accession: | Q9Y6X9.2 |
| UniProt Secondary Accession: | Q9Y6X9,Q9UF28, Q9Y6V2, B2RNB1, |
| UniProt Related Accession: | Q9Y6X9 |
| Molecular Weight: | 110,724 Da |
| NCBI Full Name: | MORC family CW-type zinc finger protein 2 |
| NCBI Synonym Full Names: | MORC family CW-type zinc finger 2 |
| NCBI Official Symbol: | MORC2 |
| NCBI Official Synonym Symbols: | ZCW3; CMT2Z; ZCWCC1 |
| NCBI Protein Information: | MORC family CW-type zinc finger protein 2 |
| UniProt Protein Name: | MORC family CW-type zinc finger protein 2 |
| UniProt Synonym Protein Names: | Zinc finger CW-type coiled-coil domain protein 1 |
| Protein Family: | MORC family CW-type zinc finger protein |
| UniProt Gene Name: | MORC2 |
| UniProt Entry Name: | MORC2_HUMAN |