Anti-Monoamine Oxidase B Antibody (CAB11597)
- SKU:
- CAB11597
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-Monoamine Oxidase B Antibody |
| 抗体コード: | CAB11597 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Monoamine Oxidase B |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, HepG2 |
| 免疫原: | A synthesized peptide derived from human Monoamine Oxidase B |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 4129 |
| Uniprot: | P27338 |
| セルラーロケーション: | |
| 計算された分子量: | 59kDa |
| 観察された分子量: | 59KDa |
 | Western blot - Monoamine Oxidase B Rabbit mAb (CAB11597) |
| 同義語: | |
| バックグラウンド: | The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Amino Acid Metabolism - arginine and proline; EC 1.4.3.4; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - histidine; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tryptophan Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane Molecular Function:amine oxidase activity; protein homodimerization activity; electron carrier activity; FAD binding Biological Process: response to drug; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to selenium ion; response to ethanol; substantia nigra development; dopamine catabolic process; response to toxin; xenobiotic metabolic process; response to lipopolysaccharide; hydrogen peroxide biosynthetic process; response to corticosterone stimulus; response to aluminum ion |
| NCBI Summary: | The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P27338 |
| NCBI GenInfo Identifier: | 113980 |
| NCBI Gene ID: | 4129 |
| NCBI Accession: | P27338.3 |
| UniProt Secondary Accession: | P27338,Q7Z6S2, B2R6R3, B7Z5H3, D3DWC3, |
| UniProt Related Accession: | P27338 |
| Molecular Weight: | 520 |
| NCBI Full Name: | Amine oxidase |
| NCBI Synonym Full Names: | monoamine oxidase B |
| NCBI Official Symbol: | MAOB |
| NCBI Protein Information: | amine oxidase [flavin-containing] B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B |
| UniProt Protein Name: | Amine oxidase [flavin-containing] B |
| UniProt Synonym Protein Names: | Monoamine oxidase type B; MAO-B |
| Protein Family: | Amine oxidase |
| UniProt Gene Name: | MAOB |
| UniProt Entry Name: | AOFB_HUMAN |