Anti-MOAP1 Antibody (CAB5759)
- SKU:
- CAB5759
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | Anti-MOAP1 Antibody |
| 抗体コード: | CAB5759 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | MCF7 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MTLR LLED WCRG MDMN PRKA LLIA GISQ SCSV AEIE EALQ AGLA PLGE YRLL GRMF RRDE NRKV ALVG LTAE TSHA LVPK EIPG KGGI WRVI FKPP DPDN TFLS RLNE FLAG EGMT VGEL SRAL GHEN GSLD PEQG MIPE MWAP MLAQ ALEA LQPA LQCL KYKK LRVF SGRE SPEP GEEE FGRW MFHT TQMI KAWQ VPDV EKRR RLLE SLRG PALD VIRV LKIN NPLI TVDE CLQA LEEV FGVT DNPR ELQV KYLT TYQK DEEK LSAY VLRL EPLL QKLV QRGA IERD AVNQ ARLD QVIA GAVH KTIR RELN LPED GPAP GFLQ LLVL IKDY EAAE EEEA LLQA ILEG NFT |
| 遺伝子ID: | 64112 |
| Uniprot: | Q96BY2 |
| セルラーロケーション: | |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 39kDa |
| 同義語: | MOAP1, MAP-1, PNMA4 |
| バックグラウンド: | The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. |
| UniProt Protein Function: | MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q32 Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol Molecular Function:protein binding; ubiquitin protein ligase binding Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; protein insertion into mitochondrial membrane during induction of apoptosis; positive regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96BY2 |
| NCBI GenInfo Identifier: | 19923584 |
| NCBI Gene ID: | 64112 |
| NCBI Accession: | NP_071434.2 |
| UniProt Secondary Accession: | Q96BY2,Q9H833, Q9HAS1, B2RDF6, |
| UniProt Related Accession: | Q96BY2 |
| Molecular Weight: | 39,513 Da |
| NCBI Full Name: | modulator of apoptosis 1 |
| NCBI Synonym Full Names: | modulator of apoptosis 1 |
| NCBI Official Symbol: | MOAP1 |
| NCBI Official Synonym Symbols: | MAP-1; PNMA4 |
| NCBI Protein Information: | modulator of apoptosis 1; MAP1; paraneoplastic Ma antigen family member 4; paraneoplastic antigen Ma4; paraneoplastic antigen like 4 |
| UniProt Protein Name: | Modulator of apoptosis 1 |
| UniProt Synonym Protein Names: | Paraneoplastic antigen Ma4 |
| Protein Family: | Modulator of apoptosis |
| UniProt Gene Name: | MOAP1 |
| UniProt Entry Name: | MOAP1_HUMAN |
 | Western blot analysis of extracts of MCF-7 cells, using MOAP1 antibody (CAB5759) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 120s. |
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