Anti-MMEL1 Antibody (CAB15188)
- SKU:
- CAB15188
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MMEL1 Antibody |
抗体コード: | CAB15188 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MMEL1 (NP_258428.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 293T, OVCAR3 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MMEL1 (NP_258428.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NWTL FIQT VLSS VKIK LLPD EEVV VYGI PYLQ NLEN IIDT YSAR TIQN YLVW RLVL DRIG SLSQ RFKD TRVN YRKA LFGT MVEE VRWR ECVG YVNS NMEN A |
遺伝子ID: | 79258 |
Uniprot: | Q495T6 |
セルラーロケーション: | Membrane, Secreted, Single-pass type II membrane protein |
計算された分子量: | 69kDa/71kDa/89kDa |
観察された分子量: | 99kDa |
同義語: | MMEL1, MMEL2, NEP2, NEPII, NL1, NL2, SEP |
バックグラウンド: | The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. |
UniProt Protein Function: | MELL1: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond. Belongs to the peptidase M13 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.24.11; Membrane protein, integral; Protease Chromosomal Location of Human Ortholog: 1p36.32 |
NCBI Summary: | The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q495T6 |
NCBI GenInfo Identifier: | 239049391 |
NCBI Gene ID: | 79258 |
NCBI Accession: | NP_258428.2 |
UniProt Secondary Accession: | Q495T6,Q495T7, Q495T8, Q5SZS6, Q96PH9, B9DI79, |
UniProt Related Accession: | Q495T6 |
Molecular Weight: | 89.4 |
NCBI Full Name: | membrane metallo-endopeptidase-like 1 |
NCBI Synonym Full Names: | membrane metalloendopeptidase like 1 |
NCBI Official Symbol: | MMEL1 |
NCBI Official Synonym Symbols: | NL1; NL2; SEP; NEP2; MMEL2; NEPII |
NCBI Protein Information: | membrane metallo-endopeptidase-like 1 |
UniProt Protein Name: | Membrane metallo-endopeptidase-like 1 |
UniProt Synonym Protein Names: | Membrane metallo-endopeptidase-like 2; NEP2(m); Neprilysin II; NEPII |
Protein Family: | NEDD8-specific protease |
UniProt Gene Name: | MMEL1 |
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