Anti-MKRN3 Antibody (CAB16073)
- SKU:
- CAB16073
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-MKRN3 Antibody |
| 抗体コード: | CAB16073 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human MKRN3 (NP_005655.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human MKRN3 (NP_005655.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEEP AAPS EAHE AAGA QAGA EAAR EGVS GPDL PVCE PSGE SAAP DSAL PHAA RGWA PFPV APVP AHLR RGGL RPAP ASGG GAWP SPLP SRSS GIWT KQII CRYY IHGQ CKEG ENCR YSHD LSGR KMAT EGGV SPPG ASAG GGPS TAAH IEPP TQEV AEAP PAAS SLSL PVIG SAAE RGFF EAER DNAD RGAA GGAG VESW ADAI EFVP GQPY RGRW VASA PEAP LQSS ETER KQMA VGSG LRFC YYAS RGVC FRGE SCMY |
| 遺伝子ID: | 7681 |
| Uniprot: | Q13064 |
| セルラーロケーション: | |
| 計算された分子量: | 55kDa |
| 観察された分子量: | 56kDa |
| 同義語: | MKRN3, CPPB2, D15S9, RNF63, ZFP127, ZNF127 |
| バックグラウンド: | The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. |
| UniProt Protein Function: | MKRN3: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. |
| UniProt Protein Details: | Protein type:EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase Chromosomal Location of Human Ortholog: 15q11.2 Cellular Component: intracellular ribonucleoprotein complex Molecular Function:identical protein binding; metal ion binding; protein binding; transferase activity Biological Process: protein ubiquitination Disease: Prader-willi Syndrome; Precocious Puberty, Central, 2 |
| NCBI Summary: | The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13064 |
| NCBI GenInfo Identifier: | 5032243 |
| NCBI Gene ID: | 7681 |
| NCBI Accession: | NP_005655.1 |
| UniProt Related Accession: | Q13064 |
| Molecular Weight: | 55,645 Da |
| NCBI Full Name: | probable E3 ubiquitin-protein ligase makorin-3 |
| NCBI Synonym Full Names: | makorin ring finger protein 3 |
| NCBI Official Symbol: | MKRN3 |
| NCBI Official Synonym Symbols: | CPPB2; D15S9; RNF63; ZFP127; ZNF127 |
| NCBI Protein Information: | probable E3 ubiquitin-protein ligase makorin-3 |
| UniProt Protein Name: | Probable E3 ubiquitin-protein ligase makorin-3 |
| UniProt Synonym Protein Names: | RING finger protein 63; RING-type E3 ubiquitin transferase makorin-3Curated; Zinc finger protein 127 |
| Protein Family: | Probable E3 ubiquitin-protein ligase makorin |
| UniProt Gene Name: | MKRN3 |
 | Western blot analysis of extracts of mouse kidney, using MKRN3 antibody (CAB16073) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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