Anti-Mitofusin 2 Antibody (CAB13606)
- SKU:
- CAB13606
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-Mitofusin 2 Antibody |
| 抗体コード: | CAB13606 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | QVQQ ELSG TFAH LCQQ VDIT RDNL EQEI AAMN KKVE ALDS LQSR AKLL RNKA GWLD SELN MFTH QYLQ PSR |
| 遺伝子ID: | 170731 |
| Uniprot: | |
| セルラーロケーション: | Mitochondrion outer membrane, Multi-pass membrane protein |
| 計算された分子量: | 68kDa/86kDa |
| 観察された分子量: | 86kDa |
| 同義語: | MFN2, CMT2A, CMT2A2, CMT2A2A, CMT2A2B, CPRP1, HMSN6A, HSG, MARF, mitofusin-2 |
| バックグラウンド: | This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. |
 | Western blot analysis of extracts of various cell lines, using Mitofusin 2 Antibody (CAB13606) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded mouse liver using Mitofusin 2 antibody (CAB13606) (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver damage using Mitofusin 2 antibody (CAB13606) (40x lens). |
 | Immunohistochemistry of paraffin-embedded human esophagus using Mitofusin 2 antibody (CAB13606) (40x lens). |