Anti-MIER1 Antibody (CAB18480)
- SKU:
- CAB18480
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-MIER1 Antibody |
| 抗体コード: | CAB18480 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human MIER1. |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, A-549, Mouse brain |
| 免疫原: | Recombinant protein of human MIER1. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 57708 |
| Uniprot: | Q8N108 |
| セルラーロケーション: | |
| 計算された分子量: | 9kDa/42-63kDa |
| 観察された分子量: | 58kDa |
 | Western blot - MIER1 Rabbit pAb (CAB18480) |
| 同義語: | ER1, MI-ER1, MIER1 |
| バックグラウンド: | This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. |
| UniProt Protein Function: | MIER1: a transcriptional repressor which acts through recruitment of HDAC1. Contains a Myb-like DNA-binding and ELM2 domain. Its expression is associated with breast carcinoma |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1p31.3 Cellular Component: nucleoplasm; transcriptional repressor complex Molecular Function:protein binding; signal transducer activity Biological Process: positive regulation of chromatin silencing; positive regulation of I-kappaB kinase/NF-kappaB cascade |
| NCBI Summary: | This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013] |
| UniProt Code: | Q8N108 |
| NCBI GenInfo Identifier: | 380865399 |
| NCBI Gene ID: | 57708 |
| NCBI Accession: | Q8N108.2 |
| UniProt Secondary Accession: | Q8N108,Q08AE0, Q32NC4, Q5T104, Q5TAD1, Q5TAD2, Q5TAD4 Q5TAD5, Q6AHY8, Q86TB4, Q8N156, C9JFD4, |
| UniProt Related Accession: | Q8N108 |
| Molecular Weight: | 9,357 Da |
| NCBI Full Name: | Mesoderm induction early response protein 1 |
| NCBI Synonym Full Names: | MIER1 transcriptional regulator |
| NCBI Official Symbol: | MIER1 |
| NCBI Official Synonym Symbols: | ER1; MI-ER1 |
| NCBI Protein Information: | mesoderm induction early response protein 1 |
| UniProt Protein Name: | Mesoderm induction early response protein 1 |
| Protein Family: | Mesoderm induction early response protein |
| UniProt Gene Name: | MIER1 |
| UniProt Entry Name: | MIER1_HUMAN |