Anti-MGAT5 Antibody (CAB10567)
- SKU:
- CAB10567
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MGAT5 Antibody |
| 抗体コード: | CAB10567 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 627-741 of human MGAT5 (NP_002401.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | LO2, 293T, Raji, Jurkat |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 627-741 of human MGAT5 (NP_002401.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | HGQV MWPP LSAL QVKL AEPG QSCK QVCQ ESQL ICEP SFFQ HLNK DKDM LKYK VTCQ SSEL AKDI LVPS FDPK NKHC VFQG DLLL FSCA GAHP RHQR VCPC RDFI KGQV ALCK DCL |
| 遺伝子ID: | 4249 |
| Uniprot: | Q09328 |
| セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
| 計算された分子量: | 84kDa |
| 観察された分子量: | 115kDa |
| 同義語: | MGAT5, GNT-V, GNT-VA, alpha-1 |
| バックグラウンド: | The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1, 6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. |
| UniProt Protein Function: | Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. |
| NCBI Summary: | The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q09328 |
| NCBI GenInfo Identifier: | 4505167 |
| NCBI Gene ID: | 4249 |
| NCBI Accession: | NP_002401.1 |
| UniProt Secondary Accession: | Q09328,D3DP70, |
| UniProt Related Accession: | Q09328 |
| Molecular Weight: | 84,543 Da |
| NCBI Full Name: | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A |
| NCBI Synonym Full Names: | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| NCBI Official Symbol: | MGAT5 |
| NCBI Official Synonym Symbols: | GNT-V; GNT-VA |
| NCBI Protein Information: | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A |
| UniProt Protein Name: | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A |
| UniProt Synonym Protein Names: | Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GlcNAc-T V; GNT-V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V |
| Protein Family: | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase |
| UniProt Gene Name: | MGAT5 |
 | Western blot analysis of extracts of various cell lines, using MGAT5 antibody (CAB10567) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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