Anti-MGAT3 Antibody (CAB8134)
- SKU:
- CAB8134
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | MGAT3 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8134 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 364-533 of human MGAT3 (NP_002400.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SW620, U-251MG, SKOV3 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 364-533 of human MGAT3 (NP_002400.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GCTV DMLQ AVYG LDGI RLRR RQYY TMPN FRQY ENRT GHIL VQWS LGSP LHFA GWHC SWCF TPEG IYFK LVSA QNGD FPRW GDYE DKRD LNYI RGLI RTGG WFDG TQQE YPPA DPSE HMYA PKYL LKNY DRFH YLLD NPYQ EPRS TAAG GWRH RGPE GRPP ARGK LDEA EV |
| 遺伝子ID: | 4248 |
| Uniprot: | Q09327 |
| セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
| 計算された分子量: | 61kDa |
| 観察された分子量: | 61kDa |
| 同義語: | MGAT3, GNT-III, GNT3, beta-1 |
| バックグラウンド: | There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| UniProt Protein Function: | MGAT3: It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Belongs to the glycosyltransferase 17 family. |
| UniProt Protein Details: | Protein type:Glycan Metabolism - N-glycan biosynthesis; Transferase; EC 2.4.1.144; Membrane protein, integral Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: Golgi membrane; integral to membrane Molecular Function:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Biological Process: cellular protein metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
| NCBI Summary: | There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q09327 |
| NCBI GenInfo Identifier: | 61252497 |
| NCBI Gene ID: | 4248 |
| NCBI Accession: | Q09327.3 |
| UniProt Secondary Accession: | Q09327,Q14CK5, Q6IC49, Q9UH32, A6NGD0, |
| UniProt Related Accession: | Q09327 |
| Molecular Weight: | 61,313 Da |
| NCBI Full Name: | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
| NCBI Synonym Full Names: | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| NCBI Official Symbol: | MGAT3 |
| NCBI Official Synonym Symbols: | GNT3; GNT-III |
| NCBI Protein Information: | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase; GlcNAc-T III; N-acetylglucosaminyltransferase III; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III |
| UniProt Protein Name: | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
| UniProt Synonym Protein Names: | N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; GNT-III; GlcNAc-T III; N-acetylglucosaminyltransferase III |
| Protein Family: | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
| UniProt Gene Name: | MGAT3 |
| UniProt Entry Name: | MGAT3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MGAT3 antibody (CAB8134) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
 | Immunohistochemistry of paraffin-embedded rat heart using MGAT3 antibody (CAB8134) at dilution of 1:100 (40x lens). |
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