Anti-MEPCE Antibody (CAB7121)
- SKU:
- CAB7121
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MEPCE Antibody |
| 抗体コード: | CAB7121 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 470-689 of human MEPCE (NP_062552.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 470-689 of human MEPCE (NP_062552.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MVGL DIDS RLIH SARQ NIRH YLSE ELRL PPQT LEGD PGAE GEEG TTTV RKRS CFPA SLTA SRGP IAAP QVPL DGAD TSVF PNNV VFVT GNYV LDRD DLVE AQTP EYDV VLCL SLTK WVHL NWGD EGLK RMFR RIYR HLRP GGIL VLEP QPWS SYGK RKTL TETI YKNY YRIQ LKPE QFSS YLTS PDVG FSSY ELVA TPHN TSKG FQRP VYLF HKAR SPSH |
| 遺伝子ID: | 56257 |
| Uniprot: | Q7L2J0 |
| セルラーロケーション: | |
| 計算された分子量: | 24kDa/74kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | MEPCE, BCDIN3 |
| バックグラウンド: |
| UniProt Protein Function: | BCDIN3: a CDK9-associated enzyme that forms the distinctive gamma-methylphosphate cap structure of 7SK, a noncoding RNA that regulates CDK9 activity. An adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to its stabilization. Component of the 7SK snRNP complex that contains P-TEFb (composed of CDK9 and CCNT1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs. Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues. Contains a Bin3 domain found in a number of protein methyltransferases that modify RNA-binding proteins. |
| UniProt Protein Details: | Protein type:Transcription regulation; Methyltransferase; RNA processing; EC 2.1.1.; EC 2.1.1.- Chromosomal Location of Human Ortholog: 7q22.1 Molecular Function:RNA methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity Biological Process: RNA methylation; snRNA metabolic process; snRNA modification |
| UniProt Code: | Q7L2J0 |
| NCBI GenInfo Identifier: | 74758999 |
| NCBI Gene ID: | 56257 |
| NCBI Accession: | Q7L2J0.1 |
| UniProt Secondary Accession: | Q7L2J0,Q9NPD4, B3KP86, D6W5V7, |
| UniProt Related Accession: | Q7L2J0 |
| Molecular Weight: | 24,950 Da |
| NCBI Full Name: | 7SK snRNA methylphosphate capping enzyme |
| NCBI Synonym Full Names: | methylphosphate capping enzyme |
| NCBI Official Symbol: | MEPCE |
| NCBI Official Synonym Symbols: | BCDIN3 |
| NCBI Protein Information: | 7SK snRNA methylphosphate capping enzyme |
| UniProt Protein Name: | 7SK snRNA methylphosphate capping enzyme |
| UniProt Synonym Protein Names: | Bicoid-interacting protein 3 homolog; Bin3 homolog |
| Protein Family: | 7SK snRNA methylphosphate capping enzyme |
| UniProt Gene Name: | MEPCE |
| UniProt Entry Name: | MEPCE_HUMAN |
 | Immunofluorescence analysis of A549 cells using MEPCE antibody (CAB7121). |
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