Anti-MED30 Antibody (CAB13135)
- SKU:
- CAB13135
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-MED30 Antibody |
抗体コード: | CAB13135 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-178 of human MED30 (NP_542382.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-178 of human MED30 (NP_542382.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSTP PLAA SGMA PGPF AGPQ AQQA AREV NTAS LCRI GQET VQDI VYRT MEIF QLLR NMQL PNGV TYHT GTYQ DRLT KLQD NLRQ LSVL FRKL RLVY DKCN ENCG GMDP IPVE QLIP YVEE DGSK NDDR AGPP RFAS EERR EIAE VNKK LKQK NQQL KQIM DQLR NLIW DINA MLAM RN |
遺伝子ID: | 90390 |
Uniprot: | Q96HR3 |
セルラーロケーション: | Nucleus |
計算された分子量: | 16kDa/20kDa |
観察された分子量: | 30kDa |
同義語: | MED30, MED30S, THRAP6, TRAP25 |
バックグラウンド: |
UniProt Protein Function: | MED30: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 30 family. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 8q24.11 Cellular Component: nucleoplasm; nucleus; Srb-mediator complex Molecular Function:protein binding; receptor activity; thyroid hormone receptor binding; transcription cofactor activity Biological Process: androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; steroid hormone receptor signaling pathway; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010] |
UniProt Code: | Q96HR3 |
NCBI GenInfo Identifier: | 74731968 |
NCBI Gene ID: | 90390 |
NCBI Accession: | Q96HR3.1 |
UniProt Secondary Accession: | Q96HR3,C6GKU9, |
UniProt Related Accession: | Q96HR3 |
Molecular Weight: | 16,279 Da |
NCBI Full Name: | Mediator of RNA polymerase II transcription subunit 30 |
NCBI Synonym Full Names: | mediator complex subunit 30 |
NCBI Official Symbol: | MED30 |
NCBI Official Synonym Symbols: | MED30S; THRAP6; TRAP25 |
NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 30 |
UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 30 |
UniProt Synonym Protein Names: | Mediator complex subunit 30; TRAP/Mediator complex component TRAP25; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associated protein complex 25 kDa component; Trap25 |
Protein Family: | Mediator of RNA polymerase II transcription |
UniProt Gene Name: | MED30 |
UniProt Entry Name: | MED30_HUMAN |
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