Anti-MCHR1 Antibody (CAB18111)
- SKU:
- CAB18111
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-MCHR1 Antibody |
| 抗体コード: | CAB18111 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human MCHR1. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain, Rat heart |
| 免疫原: | Recombinant protein of human MCHR1. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2847 |
| Uniprot: | Q99705 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 46kDa |
 | Western blot - MCHR1 Polyclonal Antibody (CAB18111) |
| 同義語: | GPR24, MCH-1R, MCH1R, SLC-1, SLC1, MCHR1 |
| バックグラウンド: |
| UniProt Protein Function: | MCHR1: Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane Molecular Function:G-protein coupled receptor activity; protein C-terminus binding; neuropeptide receptor activity; hormone binding; melanin-concentrating hormone receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; generation of precursor metabolites and energy; neuropeptide signaling pathway; feeding behavior; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of calcium ion transport |
| NCBI Summary: | The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99705 |
| NCBI GenInfo Identifier: | 88758590 |
| NCBI Gene ID: | 2847 |
| NCBI Accession: | NP_005288.3 |
| UniProt Secondary Accession: | Q99705,Q5R3J1, Q96S47, Q9BV08, B2RBX6, |
| UniProt Related Accession: | Q99705 |
| Molecular Weight: | 45,963 Da |
| NCBI Full Name: | melanin-concentrating hormone receptor 1 |
| NCBI Synonym Full Names: | melanin-concentrating hormone receptor 1 |
| NCBI Official Symbol: | MCHR1 |
| NCBI Official Synonym Symbols: | SLC1; GPR24; MCH1R; SLC-1; MCH-1R |
| NCBI Protein Information: | melanin-concentrating hormone receptor 1; MCH receptor 1; G protein-coupled receptor 24; somatostatin receptor-like protein |
| UniProt Protein Name: | Melanin-concentrating hormone receptor 1 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 24; MCH-1R; MCH1R; MCHR; SLC-1; Somatostatin receptor-like protein |
| Protein Family: | Melanin-concentrating hormone receptor |
| UniProt Gene Name: | MCHR1 |
| UniProt Entry Name: | MCHR1_HUMAN |