Anti-MAPRE2 Antibody (CAB6649)
- SKU:
- CAB6649
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-MAPRE2 Antibody |
| 抗体コード: | CAB6649 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human MAPRE2 (NP_001137298.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse kidney, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human MAPRE2 (NP_001137298.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAVN VYST SITQ ETMS RHDI IAWV NDIV SLNY TKVE QLCS GAAY CQFM DMLF PGCI SLKK VKFQ AKLE HEYI HNFK LLQA SFKR MNVD KVIP VEKL VKGR FQDN LDFI QWFK KFYD ANYD GKEY DPVE ARQG QDAI PPPD PGEQ IFNL PKKS HHAN SPTA GAAK SSPA AKPG STPS RPSS AKRA SSSG SASK SDKD LETQ VIQL NEQV HSLK LALE GVEK ERDF YFGK LREI ELLC QEHG QEND DLVQ RLMD ILYA SEEH EGHT EEPE AEEQ AHEQ QPPQ QEEY |
| 遺伝子ID: | 10982 |
| Uniprot: | Q15555 |
| セルラーロケーション: | Cytoplasm, cytoskeleton |
| 計算された分子量: | 29kDa/30kDa/32kDa/35kDa/37kDa |
| 観察された分子量: | 32KDa |
| 同義語: | MAPRE2, CSCSC2, EB1, EB2, RP1 |
| バックグラウンド: | The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. |
| UniProt Protein Function: | RP1: shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Its function is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 18q12.1 Cellular Component: microtubule cytoskeleton; cytoplasm Molecular Function:microtubule binding Biological Process: mitosis; cell proliferation; cell division; signal transduction |
| NCBI Summary: | The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q15555 |
| NCBI GenInfo Identifier: | 60390165 |
| NCBI Gene ID: | 10982 |
| NCBI Accession: | Q15555.1 |
| UniProt Secondary Accession: | Q15555,Q9UQ33, B2RE21, B3KR39, B4DJV4, B7Z2L3, E9PHR3 F5H1V8, G5E9I6, |
| UniProt Related Accession: | Q15555 |
| Molecular Weight: | 327 |
| NCBI Full Name: | Microtubule-associated protein RP/EB family member 2 |
| NCBI Synonym Full Names: | microtubule-associated protein, RP/EB family, member 2 |
| NCBI Official Symbol: | MAPRE2 |
| NCBI Official Synonym Symbols: | EB1; EB2; RP1 |
| NCBI Protein Information: | microtubule-associated protein RP/EB family member 2; end-binding protein 2; APC-binding protein EB1; APC-binding protein EB2; T-cell activation protein, EB1 family |
| UniProt Protein Name: | Microtubule-associated protein RP/EB family member 2 |
| UniProt Synonym Protein Names: | APC-binding protein EB2; End-binding protein 2; EB2 |
| Protein Family: | Microtubule-associated protein RP/EB family |
| UniProt Gene Name: | MAPRE2 |
| UniProt Entry Name: | MARE2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MAPRE2 antibody (CAB6649) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of HeLa cells using MAPRE2 antibody (CAB6649). Blue: DAPI for nuclear staining. |
View AllClose