Anti-MAPK6 Antibody (CAB15304)[KO Validated]
![Anti-MAPK6 Antibody (CAB15304)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/18282/18149/anti-mapk6-antibody-cab15304ko-validated__27861__05556.1645803925.jpg?c=1 "Anti-MAPK6 Antibody (CAB15304)[KO Validated]")
- SKU:
- CAB15304
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
![Anti-MAPK6 Antibody (CAB15304)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/1280x1280/products/18282/18149/anti-mapk6-antibody-cab15304ko-validated__27861__05556.1645803925.jpg?c=1&imbypass=on "Anti-MAPK6 Antibody (CAB15304)[KO Validated]")
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Description
| 抗体名: | Anti-MAPK6 Antibody [KO Validated] |
| 抗体コード: | CAB15304 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 372-721 of human MAPK6 (NP_002739.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-251MG, A549, LO2, BxPC-3, 293T, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 372-721 of human MAPK6 (NP_002739.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NFDI DEVQ LDPR ALSD VTDE EEVQ VDPR KYLD GDRE KYLE DPAF DTNY STEP CWQY SDHH ENKY CDLE CSHT CNYK TRSS SYLD NLVW RESE VNHY YEPK LIID LSNW KEQS KEKS DKKG KSKC ERNG LVKA QIAL EEAS QQLA GKER EKNQ GFDF DSFI AGTI QLSS QHEP TDVV DKLN DLNS SVSQ LELK SLIS KSVS QEKQ EKGM ANLA QLEA LYQS SWDS QFVS GGED CFFI NQFC EVRK DEQV EKEN TYTS YLDK FFSR KEDT EMLE TEPV EDGK LGER GHEE GFLN NSGE FLFN KQLE SIGI PQFH SPVG SPLK SIQA TLTP SAMK SSPQ IPHQ TYSS ILKH LN |
| 遺伝子ID: | 5597 |
| Uniprot: | Q16659 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 82kDa |
| 観察された分子量: | 120kDa |
| 同義語: | MAPK6, ERK3, HsT17250, PRKM6, p97MAPK |
| バックグラウンド: | The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. |
| UniProt Protein Function: | ERK3: a protein kinase of the MAPK family. Plays a critical role in the regulation of cell growth and differentiation. Localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; Kinase, protein; EC 2.7.11.24; CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily Chromosomal Location of Human Ortholog: 15q21 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function:MAP kinase activity; protein binding; protein serine/threonine kinase activity Biological Process: protein amino acid phosphorylation; signal transduction |
| NCBI Summary: | The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16659 |
| NCBI GenInfo Identifier: | 2499596 |
| NCBI Gene ID: | 5597 |
| NCBI Accession: | Q16659.1 |
| UniProt Secondary Accession: | Q16659,Q68DH4, Q8IYN8, B2R945, B5BU65, |
| UniProt Related Accession: | Q16659 |
| Molecular Weight: | 82,681 Da |
| NCBI Full Name: | Mitogen-activated protein kinase 6 |
| NCBI Synonym Full Names: | mitogen-activated protein kinase 6 |
| NCBI Official Symbol: | MAPK6 |
| NCBI Official Synonym Symbols: | ERK3; PRKM6; p97MAPK; HsT17250 |
| NCBI Protein Information: | mitogen-activated protein kinase 6 |
| UniProt Protein Name: | Mitogen-activated protein kinase 6 |
| UniProt Synonym Protein Names: | Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK |
| UniProt Gene Name: | MAPK6 |
| UniProt Entry Name: | MK06_HUMAN |
![Anti-MAPK6 Antibody [KO Validated] (CAB15304)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/m/789/A15304_1__33815.jpg) | Western blot analysis of extracts of various cell lines, using MAPK6 antibody (CAB15304) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
![Anti-MAPK6 Antibody [KO Validated] (CAB15304)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/v/867/A15304_2__78734.jpg) | Western blot analysis of extracts from normal (control) and MAPK6 knockout (KO) HeLa cells, using MAPK6 antibody (CAB15304) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
![Anti-MAPK6 Antibody [KO Validated] (CAB15304)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/g/287/A15304_3__97240.jpg) | Immunofluorescence analysis of L929 cells using MAPK6 Polyclonal Antibody (CAB15304) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |