Anti-MAN1C1 Antibody (CAB12837)

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SKU:
CAB12837
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-MAN1C1 Antibody
抗体コード:CAB12837
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse
ポジティブサンプル:A-549, U-87MG, HepG2, Mouse liver
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:PHSS RLKR LFLA PRTQ QPGL EVVA EIAG HAPA REQE PPPN PAPA APAP GEDD PSSW ASPR RRKG GLRR TRPT GPRE EATA ARGN SIPA SRPG DEGV PFRF DFNA FRSR LRHP VLGT RADE SQEP QSQV RAQR EKIK EMMQ FAWQ SYKR YAMG KNEL RPLT KDGY EGNM FGGL SGAT VIDS LDTL YLME LKEE FQEA K
遺伝子ID:57134
Uniprot:Q9NR34
セルラーロケーション:Golgi apparatus membrane, Single-pass type II membrane protein
計算された分子量:70kDa
観察された分子量:68kDa
同義語:MAN1C1, HMIC, MAN1A3, MAN1C, pp6318
バックグラウンド:
UniProt Protein Function:MAN1C1: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. Belongs to the glycosyl hydrolase 47 family.
UniProt Protein Details:

Protein type:Calcium-binding; EC 3.2.1.113; Glycan Metabolism - N-glycan biosynthesis; Hydrolase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: endoplasmic reticulum; Golgi membrane; integral to Golgi membrane

Molecular Function:calcium ion binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

Biological Process: N-glycan processing; protein amino acid N-linked glycosylation

UniProt Code:Q9NR34
NCBI GenInfo Identifier:17369308
NCBI Gene ID:57134
NCBI Accession:Q9NR34.1
UniProt Secondary Accession:Q9NR34,Q9Y545, A6NNE2, B2RNP2,
UniProt Related Accession:Q9NR34
Molecular Weight:71kDa
NCBI Full Name:Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
NCBI Synonym Full Names:mannosidase alpha class 1C member 1
NCBI Official Symbol:MAN1C1  
NCBI Official Synonym Symbols:HMIC; MAN1C; MAN1A3; pp6318  
NCBI Protein Information:mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
UniProt Protein Name:Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
UniProt Synonym Protein Names:HMIC; Mannosidase alpha class 1C member 1; Processing alpha-1,2-mannosidase IC; Alpha-1,2-mannosidase IC
Protein Family:Mannosyl-oligosaccharide 1,2-alpha-mannosidase
UniProt Gene Name:MAN1C1  
Anti-MAN1C1 Antibody (CAB12837)Western blot analysis of extracts of various cell lines, using MAN1C1 antibody (CAB12837) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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