Anti-MAN1A1 Antibody (CAB10830)
- SKU:
- CAB10830
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MAN1A1 Antibody |
抗体コード: | CAB10830 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-190 of human MAN1A1 (NP_005898.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, LO2, Raji, A-549 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-190 of human MAN1A1 (NP_005898.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SGVL FHSS PALQ PAAD HKPG PGAR AEDA AEGR ARRR EEGA PGDP EAAL EDNL ARIR ENHE RALR EAKE TLQK LPEE IQRD ILLE KKKV AQDQ LRDK APFR GLPP VDFV PPIG VESR EPAD A |
遺伝子ID: | 4121 |
Uniprot: | P33908 |
セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
計算された分子量: | 40kDa/72kDa |
観察された分子量: | 73kDa |
同義語: | MAN1A1, HUMM3, HUMM9, MAN9 |
バックグラウンド: | This gene encodes a class I mammalian Golgi 1, 2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. |
UniProt Protein Function: | MAN1A1: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). Belongs to the glycosyl hydrolase 47 family. |
UniProt Protein Details: | Protein type:Endoplasmic reticulum; Calcium-binding; EC 3.2.1.113; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Hydrolase Chromosomal Location of Human Ortholog: 6q22 Cellular Component: Golgi membrane; Golgi apparatus; membrane; endoplasmic reticulum; cytoplasm; ER-Golgi intermediate compartment; integral to membrane Molecular Function:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; calcium ion binding; mannosidase activity Biological Process: cellular protein metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
NCBI Summary: | This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. [provided by RefSeq, Jul 2012] |
UniProt Code: | P33908 |
NCBI GenInfo Identifier: | 62906886 |
NCBI Gene ID: | 4121 |
NCBI Accession: | P33908.3 |
UniProt Secondary Accession: | P33908,P45700, |
UniProt Related Accession: | P33908 |
Molecular Weight: | 72,969 Da |
NCBI Full Name: | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA |
NCBI Synonym Full Names: | mannosidase, alpha, class 1A, member 1 |
NCBI Official Symbol: | MAN1A1 |
NCBI Official Synonym Symbols: | MAN9; HUMM3; HUMM9 |
NCBI Protein Information: | mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; Man9-mannosidase; alpha-1,2-mannosidase IA; man(9)-alpha-mannosidase; processing alpha-1,2-mannosidase IA |
UniProt Protein Name: | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA |
UniProt Synonym Protein Names: | Man(9)-alpha-mannosidase; Man9-mannosidase; Mannosidase alpha class 1A member 1; Processing alpha-1,2-mannosidase IA |
Protein Family: | Mannosyl-oligosaccharide 1,2-alpha-mannosidase |
UniProt Gene Name: | MAN1A1 |
UniProt Entry Name: | MA1A1_HUMAN |
View AllClose