Anti-MAGEA11 Antibody (CAB15288)
- SKU:
- CAB15288
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MAGEA11 Antibody |
| 抗体コード: | CAB15288 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human MAGEA11 (NP_005357.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A375, A549, OVCAR3 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human MAGEA11 (NP_005357.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | METQ FRRG GLGC SPAS IKRK KKRE DSGD FGLQ VSTM FSED DFQS TERA PYGP QLQW SQDL PRVQ VFRE QANL EDRS PRRT QRIT GGEQ VLWG PITQ IFPT VRPA DLTR VI |
| 遺伝子ID: | 4110 |
| Uniprot: | P43364 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 44kDa/48kDa |
| 観察された分子量: | 48kDa |
| 同義語: | MAGEA11, CT1.11, MAGE-11, MAGE11, MAGEA-11 |
| バックグラウンド: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression. |
| NCBI Summary: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P43364 |
| NCBI GenInfo Identifier: | 61744473 |
| NCBI Gene ID: | 4110 |
| NCBI Accession: | NP_001011544.1 |
| UniProt Secondary Accession: | P43364,Q5ETU4, Q6ZRZ5, |
| UniProt Related Accession: | P43364 |
| Molecular Weight: | 47 |
| NCBI Full Name: | melanoma-associated antigen 11 isoform b |
| NCBI Synonym Full Names: | MAGE family member A11 |
| NCBI Official Symbol: | MAGEA11 |
| NCBI Official Synonym Symbols: | CT1.11; MAGE11; MAGE-11; MAGEA-11 |
| NCBI Protein Information: | melanoma-associated antigen 11 |
| UniProt Protein Name: | Melanoma-associated antigen 11 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 1.11; CT1.11; MAGE-11 antigen |
| UniProt Gene Name: | MAGEA11 |
 | Western blot analysis of extracts of various cell lines, using MAGEA11 antibody (CAB15288) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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