Anti-LZTR1 Antibody (CAB7350)

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SKU:
CAB7350
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
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Description

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抗体名:Anti-LZTR1 Antibody
抗体コード:CAB7350
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC IF
反応性:Human, Mouse
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 300-545 of human LZTR1 (NP_006758.2).
申し込み:WB IHC IF
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
反応性:Human, Mouse
ポジティブサンプル:BT-474, SKOV3
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 300-545 of human LZTR1 (NP_006758.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:GGAA DNTL PNEL HCYD VDFQ TWEV VQPS SDSE VGGA EVPE RACA SEEV PTLT YEER VGFK KSRD VFGL DFGT TSAK QPTQ PASE LPSG RLFH AAAV ISDA MYIF GGTV DNNI RSGE MYRF QFSC YPKC TLHE DYGR LWES RQFC DVEF VLGE KEEC VQGH VAIV TARS RWLR RKIT QARE RLAQ KLEQ EAAP VPRE APGV AAGG ARPP LLHV AIRE AEAR PFEV LMQF LYTD KIKY PRKG HVED VL
遺伝子ID:8216
Uniprot:Q8N653
セルラーロケーション:
計算された分子量:94kDa
観察された分子量:110kDa
同義語:LZTR1, BTBD29, LZTR-1, NS10, SWNTS2
バックグラウンド:This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.
UniProt Protein Function:LZTR1: Probable transcriptional regulator that may play a crucial role in embryogenesis.
UniProt Protein Details:

Protein type:Transcription factor; EC 3.4.22.-

Chromosomal Location of Human Ortholog: 22q11.21|22q11.1-q11.2

Molecular Function:transcription factor activity

Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent

Disease: Schwannomatosis 2

NCBI Summary:This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
UniProt Code:Q8N653
NCBI GenInfo Identifier:29839558
NCBI Gene ID:8216
NCBI Accession:Q8N653.2
UniProt Secondary Accession:Q8N653,Q14776, Q20WK0,
UniProt Related Accession:Q8N653
Molecular Weight:840
NCBI Full Name:Leucine-zipper-like transcriptional regulator 1
NCBI Synonym Full Names:leucine-zipper-like transcription regulator 1
NCBI Official Symbol:LZTR1  
NCBI Official Synonym Symbols:BTBD29; LZTR-1; SWNTS2  
NCBI Protein Information:leucine-zipper-like transcriptional regulator 1; leucine-zipper-like regulator-1
UniProt Protein Name:Leucine-zipper-like transcriptional regulator 1
Protein Family:Leucine-zipper-like transcriptional regulator
UniProt Gene Name:LZTR1  
UniProt Entry Name:LZTR1_HUMAN
Anti-LZTR1 Antibody (CAB7350)Western blot analysis of extracts of various cell lines, using LZTR1 antibody (CAB7350) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
Anti-LZTR1 Antibody (CAB7350)Immunohistochemistry of paraffin-embedded human kidney using LZTR1 antibody (CAB7350) at dilution of 1:100 (40x lens).
Anti-LZTR1 Antibody (CAB7350)Immunofluorescence analysis of Raw264.7 cells using LZTR1 antibody (CAB7350) at dilution of 1:100. Blue: DAPI for nuclear staining.
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