Anti-LYVE1 Antibody (CAB6452)
- SKU:
- CAB6452
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-LYVE1 Antibody |
| 抗体コード: | CAB6452 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-238 of human LYVE1 (NP_006682.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse aorta, Mouse heart, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-238 of human LYVE1 (NP_006682.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LVQG SLRA EELS IQVS CRIM GITL VSKK ANQQ LNFT EAKE ACRL LGLS LAGK DQVE TALK ASFE TCSY GWVG DGFV VISR ISPN PKCG KNGV GVLI WKVP VSRQ FAAY CYNS SDTW TNSC IPEI ITTK DPIF NTQT ATQT TEFI VSDS TYSV ASPY STIP APTT TPPA PAST SIPR RKKL ICVT EVFM ETST MSTE TEPF VENK AAFK NEAA GFGG VPT |
| 遺伝子ID: | 10894 |
| Uniprot: | Q9Y5Y7 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 35kDa |
| 観察された分子量: | 33kDa |
| 同義語: | LYVE1, CRSBP-1, HAR, LYVE-1, XLKD1 |
| バックグラウンド: | This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. |
| UniProt Protein Function: | XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 11p15 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:transmembrane receptor activity; hyaluronic acid binding; receptor activity Biological Process: anatomical structure morphogenesis; glycosaminoglycan metabolic process; transport; cell-matrix adhesion; carbohydrate metabolic process; response to wounding; pathogenesis; signal transduction; cell motility; hyaluronan metabolic process; hyaluronan catabolic process |
| NCBI Summary: | This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5Y7 |
| NCBI GenInfo Identifier: | 115502898 |
| NCBI Gene ID: | 10894 |
| NCBI Accession: | Q9Y5Y7.2 |
| UniProt Secondary Accession: | Q9Y5Y7,Q8TC18, Q9UNF4, |
| UniProt Related Accession: | Q9Y5Y7 |
| Molecular Weight: | 35,213 Da |
| NCBI Full Name: | Lymphatic vessel endothelial hyaluronic acid receptor 1 |
| NCBI Synonym Full Names: | lymphatic vessel endothelial hyaluronan receptor 1 |
| NCBI Official Symbol: | LYVE1 |
| NCBI Official Synonym Symbols: | HAR; XLKD1; LYVE-1; CRSBP-1 |
| NCBI Protein Information: | lymphatic vessel endothelial hyaluronic acid receptor 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1 |
| UniProt Protein Name: | Lymphatic vessel endothelial hyaluronic acid receptor 1 |
| UniProt Synonym Protein Names: | Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor |
| Protein Family: | Lymphatic vessel endothelial hyaluronic acid receptor |
| UniProt Gene Name: | LYVE1 |
| UniProt Entry Name: | LYVE1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LYVE1 antibody (CAB6452) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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