Anti-LRRC7 Antibody (CAB13114)
- SKU:
- CAB13114
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LRRC7 Antibody |
| 抗体コード: | CAB13114 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FPQP LDSK PLLS QREA VPPG NIPQ RPDR LPMS DTFT DNWT DGSH YDNT GFVA EETT AENA NSNP LLSS KSRS TSSH GRRP LIRQ DRIV GVPL ELEQ STHR HTPE TEVP PSNP WQNW TRTP SPFE DRTA FPSK LETT PTTS PLPE RKEH IKES TEIP SPFS P |
| 遺伝子ID: | 57554 |
| Uniprot: | Q96NW7 |
| セルラーロケーション: | Cell junction, Cytoplasm, postsynaptic cell membrane, postsynaptic density, synapse |
| 計算された分子量: | 20kDa/167kDa/172kDa |
| 観察された分子量: | 172kDa |
| 同義語: | LRRC7, DENSIN |
| バックグラウンド: |
| UniProt Protein Function: | LRRC7: Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. Belongs to the LAP (LRR and PDZ) protein family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 1p31.1 Cellular Component: postsynaptic membrane; cytoplasm; postsynaptic density; cell junction Molecular Function:protein binding |
| UniProt Code: | Q96NW7 |
| NCBI GenInfo Identifier: | 16904383 |
| NCBI Gene ID: | 57554 |
| NCBI Accession: | NP_065845.1 |
| UniProt Secondary Accession: | Q96NW7,Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2 |
| UniProt Related Accession: | Q96NW7 |
| Molecular Weight: | 20,546 Da |
| NCBI Full Name: | leucine-rich repeat-containing protein 7 |
| NCBI Synonym Full Names: | leucine rich repeat containing 7 |
| NCBI Official Symbol: | LRRC7 |
| NCBI Official Synonym Symbols: | DENSIN |
| NCBI Protein Information: | leucine-rich repeat-containing protein 7; densin-180 |
| UniProt Protein Name: | Leucine-rich repeat-containing protein 7 |
| UniProt Synonym Protein Names: | Densin-180; Densin; Protein LAP1 |
| Protein Family: | Protein |
| UniProt Gene Name: | LRRC7 |
| UniProt Entry Name: | LRRC7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LRRC7 antibody (CAB13114) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of C6 cells using LRRC7 antibody (CAB13114) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of L929 cells using LRRC7 antibody (CAB13114) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of U-2 OS cells using LRRC7 antibody (CAB13114) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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