Anti-LINGO1 Antibody (CAB9369)
- SKU:
- CAB9369
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-LINGO1 Antibody |
抗体コード: | CAB9369 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-240 of human LINGO1 (NP_116197.4). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | MCF7, A-549, K-562, Mouse testis, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-240 of human LINGO1 (NP_116197.4). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | CPPR CECS AQDR AVLC HRKR FVAV PEGI PTET RLLD LGKN RIKT LNQD EFAS FPHL EELE LNEN IVSA VEPG AFNN LFNL RTLG LRSN RLKL IPLG VFTG LSNL TKLD ISEN KIVI LLDY MFQD LYNL KSLE VGDN DLVY ISHR AFSG LNSL EQLT LEKC NLTS IPTE ALSH LHGL IVLR LRHL NINA IRDY SFKR LYR |
遺伝子ID: | 84894 |
Uniprot: | Q96FE5 |
セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
計算された分子量: | 69kDa |
観察された分子量: | 70kDa |
同義語: | LINGO1, LERN1, LRRN6A, UNQ201 |
バックグラウンド: |
UniProt Protein Function: | LINGO1: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 15q24.3 Cellular Component: plasma membrane Molecular Function:epidermal growth factor receptor binding; protein binding Biological Process: axonogenesis; negative regulation of axonogenesis; signal transduction |
UniProt Code: | Q96FE5 |
NCBI GenInfo Identifier: | 50263044 |
NCBI Gene ID: | 84894 |
NCBI Accession: | NP_116197 |
UniProt Secondary Accession: | Q96FE5,Q6NUK3, Q6UXM3, Q6VVG0, Q6VVG1, Q6VVG2, Q8N3K5 Q96K52, D3DW80, |
UniProt Related Accession: | Q96FE5 |
Molecular Weight: | 15.1kDa (133aa) |
NCBI Full Name: | leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform a |
NCBI Synonym Full Names: | leucine rich repeat and Ig domain containing 1 |
NCBI Official Symbol: | LINGO1 |
NCBI Official Synonym Symbols: | LERN1; LRRN6A; UNQ201 |
NCBI Protein Information: | leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 |
UniProt Protein Name: | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 |
UniProt Synonym Protein Names: | Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A |
UniProt Gene Name: | LINGO1 |
UniProt Entry Name: | LIGO1_HUMAN |
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