Anti-LIM2 Antibody (CAB7909)
- SKU:
- CAB7909
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LIM2 Antibody |
| 抗体コード: | CAB7909 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-110 of human LIM2 (NP_085915.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | BT-474, HepG2, Jurkat, Mouse liver, Mouse eye, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-110 of human LIM2 (NP_085915.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TDHW MQYR LSGS FAHQ GLWR YCLG NKCY LQTD SIGE PPGQ GPGR AWGK SRAD LGAQ GHLY SRWR TLRL KEGK GATQ AYWN ATRA FM |
| 遺伝子ID: | 3982 |
| Uniprot: | P55344 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 19kDa/24kDa |
| 観察された分子量: | 20kDa |
| 同義語: | LIM2, CTRCT19, MP17, MP19 |
| バックグラウンド: | This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | MP20: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis. Belongs to the PMP-22/EMP/MP20 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.4 Disease: Cataract 19 |
| NCBI Summary: | This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| UniProt Code: | P55344 |
| NCBI GenInfo Identifier: | 17433717 |
| NCBI Gene ID: | 3982 |
| NCBI Accession: | P55344.2 |
| UniProt Secondary Accession: | P55344,Q6B083, Q9BXD0, Q9HAR5, |
| UniProt Related Accession: | P55344 |
| Molecular Weight: | 24,188 Da |
| NCBI Full Name: | Lens fiber membrane intrinsic protein |
| NCBI Synonym Full Names: | lens intrinsic membrane protein 2 |
| NCBI Official Symbol: | LIM2 |
| NCBI Official Synonym Symbols: | MP17; MP19; CTRCT19 |
| NCBI Protein Information: | lens fiber membrane intrinsic protein |
| UniProt Protein Name: | Lens fiber membrane intrinsic protein |
| UniProt Synonym Protein Names: | MP18; MP19; MP20 |
| Protein Family: | Lens fiber membrane intrinsic protein |
| UniProt Gene Name: | LIM2 |
| UniProt Entry Name: | LMIP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LIM2 antibody (CAB7909) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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