Anti-LILRA4 Antibody (CAB3396)
- SKU:
- CAB3396
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-LILRA4 Antibody |
| 抗体コード: | CAB3396 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-450 of human LILRA4 (NP_036408.4). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | LO2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-450 of human LILRA4 (NP_036408.4). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LTLQ CGSD VGYI RYTL YKEG ADGL PQRP GRQP QAGL SQAN FTLS PVSR SYGG QYRC YGAH NVSS EWSA PSDP LDIL IAGQ ISDR PSLS VQPG PTVT SGEK VTLL CQSW DPMF TFLL TKEG AAHP PLRL RSMY GAHK YQAE FPMS PVTS AHAG TYRC YGSR SSNP YLLS HPSE PLEL VVSG ATET LNPA QKKS DSKT APHL QDYT VENL IRM |
| 遺伝子ID: | 23547 |
| Uniprot: | P59901 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 47kDa/55kDa |
| 観察された分子量: | 50kDa |
| 同義語: | LILRA4, CD85g, ILT7 |
| バックグラウンド: | This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. |
| UniProt Protein Function: | LILRA4: May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: integral to membrane Molecular Function:protein binding Biological Process: immune system process |
| NCBI Summary: | This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P59901 |
| NCBI GenInfo Identifier: | 288558815 |
| NCBI Gene ID: | 23547 |
| NCBI Accession: | P59901.2 |
| UniProt Secondary Accession: | P59901,Q32MC4, |
| UniProt Related Accession: | P59901 |
| Molecular Weight: | 499 |
| NCBI Full Name: | Leukocyte immunoglobulin-like receptor subfamily A member 4 |
| NCBI Synonym Full Names: | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| NCBI Official Symbol: | LILRA4 |
| NCBI Official Synonym Symbols: | ILT7; CD85g |
| NCBI Protein Information: | leukocyte immunoglobulin-like receptor subfamily A member 4; ILT-7; immunoglobulin-like transcript 7; CD85 antigen-like family member G; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4 |
| UniProt Protein Name: | Leukocyte immunoglobulin-like receptor subfamily A member 4 |
| UniProt Synonym Protein Names: | CD85 antigen-like family member G; Immunoglobulin-like transcript 7; ILT-7; CD_antigen: CD85g |
| Protein Family: | Leukocyte immunoglobulin-like receptor subfamily |
| UniProt Gene Name: | LILRA4 |
| UniProt Entry Name: | LIRA4_HUMAN |
 | Western blot analysis of extracts of LO2 cells, using LILRA4 antibody (CAB3396) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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