Anti-LILRA1 Antibody (CAB12111)
- SKU:
- CAB12111
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-LILRA1 Antibody |
| 抗体コード: | CAB12111 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-210 of human LILRA1 (NP_006854.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | B cells, K-562, Mouse brain, Mouse lung, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-210 of human LILRA1 (NP_006854.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PRTH VQAG TLPK PTLW AEPG SVIT QGSP VTLW CQGI LETQ EYRL YREK KTAP WITR IPQE IVKK GQFP IPSI TWEH TGRY RCFY GSHT AGWS EPSD PLEL VVTG AYIK PTLS ALPS PVVT SGGN VTLH CVSQ VAFG SFIL CKEG EDEH PQCL NSQP RTHG WSRA IFSV GPVS PSRR WSYR CYAY DSNS PHVW SL |
| 遺伝子ID: | 11024 |
| Uniprot: | O75019 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 31kDa/53kDa |
| 観察された分子量: | 53kDa |
| 同義語: | LILRA1, CD85I, LIR-6, LIR6 |
| バックグラウンド: | This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | LILRA1: May act as receptor for class I MHC antigens. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: integral to membrane; plasma membrane Molecular Function:transmembrane receptor activity; antigen binding Biological Process: regulation of immune response; cell surface receptor linked signal transduction; immune system process; defense response |
| NCBI Summary: | This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
| UniProt Code: | O75019 |
| NCBI GenInfo Identifier: | 37537902 |
| NCBI Gene ID: | 11024 |
| NCBI Accession: | O75019.1 |
| UniProt Secondary Accession: | O75019,O75018, Q3MJA6, |
| UniProt Related Accession: | O75019 |
| Molecular Weight: | 31,724 Da |
| NCBI Full Name: | Leukocyte immunoglobulin-like receptor subfamily A member 1 |
| NCBI Synonym Full Names: | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| NCBI Official Symbol: | LILRA1 |
| NCBI Official Synonym Symbols: | LIR6; CD85I; LIR-6 |
| NCBI Protein Information: | leukocyte immunoglobulin-like receptor subfamily A member 1; CD85 antigen-like family member I; leukocyte immunoglobulin-like receptor 6 |
| UniProt Protein Name: | Leukocyte immunoglobulin-like receptor subfamily A member 1 |
| UniProt Synonym Protein Names: | CD85 antigen-like family member I; Leukocyte immunoglobulin-like receptor 6; LIR-6; CD_antigen: CD85i |
| Protein Family: | Leukocyte immunoglobulin-like receptor subfamily |
| UniProt Gene Name: | LILRA1 |
| UniProt Entry Name: | LIRA1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LILRA1 antibody (CAB12111) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |