Anti-LIF Antibody (CAB1288)
- SKU:
- CAB1288
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LIF Antibody |
| 抗体コード: | CAB1288 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-202 of human LIF (NP_002300.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human |
| ポジティブサンプル: | SH-SY5Y |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-202 of human LIF (NP_002300.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SPLP ITPV NATC AIRH PCHN NLMN QIRS QLAQ LNGS ANAL FILY YTAQ GEPF PNNL DKLC GPNV TDFP PFHA NGTE KAKL VELY RIVV YLGT SLGN ITRD QKIL NPSA LSLH SKLN ATAD ILRG LLSN VLCR LCSK YHVG HVDV TYGP DTSG KDVF QKKK LGCQ LLGK YKQI IAVL AQAF |
| 遺伝子ID: | 3976 |
| Uniprot: | P15018 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 9kDa/22kDa |
| 観察された分子量: | 21kDa |
| 同義語: | LIF, CDF, DIA, HILDA, MLPLI |
| バックグラウンド: | The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
| NCBI Summary: | The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
| UniProt Code: | P15018 |
| NCBI GenInfo Identifier: | 126279 |
| NCBI Gene ID: | 3976 |
| NCBI Accession: | P15018.1 |
| UniProt Secondary Accession: | P15018,Q52LZ2, B2RCW7, B5MC23, |
| UniProt Related Accession: | P15018 |
| Molecular Weight: | 9,563 Da |
| NCBI Full Name: | Leukemia inhibitory factor |
| NCBI Synonym Full Names: | LIF, interleukin 6 family cytokine |
| NCBI Official Symbol: | LIF |
| NCBI Official Synonym Symbols: | CDF; DIA; HILDA; MLPLI |
| NCBI Protein Information: | leukemia inhibitory factor |
| UniProt Protein Name: | Leukemia inhibitory factor |
| UniProt Synonym Protein Names: | Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor; MLPLI; INN: Emfilermin |
| Protein Family: | Leukemia inhibitory factor |
| UniProt Gene Name: | LIF |
 | Western blot analysis of extracts of SH-SY5Y cells, using LIF antibody (CAB1288) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded human prostate using LIF antibody (CAB1288) at dilution of 1:100 (40x lens). |
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