Anti-LHB Antibody (CAB3000)
- SKU:
- CAB3000
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-LHB Antibody |
抗体コード: | CAB3000 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide of human LHB |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | K-562 |
免疫原: | A synthetic peptide of human LHB |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 3972 |
Uniprot: | P01229 |
セルラーロケーション: | Secreted |
計算された分子量: | 15kDa |
観察された分子量: | 18kDa |
同義語: | LHB, CGB4, HH23, LSH-B, LSH-beta |
バックグラウンド: | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. |
UniProt Protein Function: | LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family. |
UniProt Protein Details: | Protein type:Hormone; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19q13.32 Cellular Component: extracellular region Molecular Function:hormone activity; receptor binding Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction Disease: Fertile Eunuch Syndrome |
NCBI Summary: | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008] |
UniProt Code: | P01229 |
NCBI GenInfo Identifier: | 1170834 |
NCBI Gene ID: | 3972 |
NCBI Accession: | P01229.3 |
UniProt Secondary Accession: | P01229,Q9UDI0, |
UniProt Related Accession: | P01229 |
Molecular Weight: | 141 |
NCBI Full Name: | Lutropin subunit beta |
NCBI Synonym Full Names: | luteinizing hormone beta polypeptide |
NCBI Official Symbol: | LHB |
NCBI Official Synonym Symbols: | CGB4; hLHB; LSH-B |
NCBI Protein Information: | lutropin subunit beta; LSH-beta; lutropin beta chain; luteinizing hormone beta subunit; interstitial cell stimulating hormone, beta chain |
UniProt Protein Name: | Lutropin subunit beta |
UniProt Synonym Protein Names: | Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta |
Protein Family: | Lutropin/choriogonadotropin |
UniProt Gene Name: | LHB |
UniProt Entry Name: | LSHB_HUMAN |
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