Anti-LGALS8 Antibody (CAB6646)
- SKU:
- CAB6646
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
| 抗体名: | Anti-LGALS8 Antibody |
| 抗体コード: | CAB6646 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-317 of human LGALS8 (NP_963838.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | BT-474, 22Rv1, Mouse liver, Mouse small intestine |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-317 of human LGALS8 (NP_963838.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VGTI PDQL DPGT LIVI RGHV PSDA DRFQ VDLQ NGSS MKPR ADVA FHFN PRFK RAGC IVCN TLIN EKWG REEI TYDT PFKR EKSF EIVI MVLK DKFQ VAVN GKHT LLYG HRIG PEKI DTLG IYGK VNIH SIGF SFSS DLQS TQAS SLEL TEIS RENV PKSG TPQL RLPF AARL NTPM GPGR TVVV KGEV NANA KSFN VDLL AGKS KDIA LHLN PRLN IKAF VRNS FLQE SWGE EERN ITSF PFSP GMYF EMII YCDV REFK VAVN GVHS LEYK HRFK ELSS IDTL EING DIHL LEVR SW |
| 遺伝子ID: | 3964 |
| Uniprot: | O00214 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 35kDa/40kDa |
| 観察された分子量: | 38kDa/50kDa |
| 同義語: | LGALS8, Gal-8, PCTA-1, PCTA1, Po66-CBP |
| バックグラウンド: | This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| UniProt Protein Function: | galectin-8: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 1q43 Cellular Component: cytosol; extracellular space; membrane Molecular Function:carbohydrate binding; protein binding |
| NCBI Summary: | This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00214 |
| NCBI GenInfo Identifier: | 292495094 |
| NCBI Gene ID: | 3964 |
| NCBI Accession: | O00214.4 |
| UniProt Secondary Accession: | O00214,O15215, Q5T3P5, Q5T3Q4, Q8TEV1, Q96B92, Q9BXC8 Q9H584, Q9H585, Q9UEZ6, Q9UP32, Q9UP33, |
| UniProt Related Accession: | O00214 |
| Molecular Weight: | 40,397 Da |
| NCBI Full Name: | Galectin-8 |
| NCBI Synonym Full Names: | galectin 8 |
| NCBI Official Symbol: | LGALS8 |
| NCBI Official Synonym Symbols: | Gal-8; PCTA1; PCTA-1; Po66-CBP |
| NCBI Protein Information: | galectin-8 |
| UniProt Protein Name: | Galectin-8 |
| UniProt Synonym Protein Names: | Po66 carbohydrate-binding protein; Po66-CBP; Prostate carcinoma tumor antigen 1; PCTA-1 |
| Protein Family: | Galectin |
| UniProt Gene Name: | LGALS8 |
| UniProt Entry Name: | LEG8_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LGALS8 antibody (CAB6646) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human colon carcinoma using LGALS8 antibody (CAB6646) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using LGALS8 antibody (CAB6646) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of A549 cells using LGALS8 antibody (CAB6646). Blue: DAPI for nuclear staining. |
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